Combined Procedures in the Treatment of Severe Acne Scars

Launched by AL-AZHAR UNIVERSITY · Jan 25, 2024

Keywords

ClinConnect Summary

This clinical trial is studying different ways to treat severe acne scars, specifically a type called atrophic acne scars, which are characterized by depressions in the skin. Researchers want to find out if combining treatments—like a procedure called subcision (which helps lift the scar), platelet-rich plasma (a treatment that uses your own blood to promote healing), special threads to support the skin, or a type of laser therapy—will work better than using any of these methods alone. The trial will run from March 2024 to March 2026, and participants will be randomly assigned to one of the treatment groups to see how effective and safe each option is.

To be eligible for the trial, participants must have severe atrophic acne scars and should not have any active acne or conditions that could complicate treatment, such as a tendency to form thick scars (keloids) or certain health issues. Pregnant or breastfeeding women, as well as those who have had recent treatments for their scars, will not be able to participate. If you join the study, you can expect to receive one of the combination treatments and will be monitored for both safety and effectiveness. This trial aims to find the best approach to help improve the appearance of severe acne scars, which could benefit many people struggling with this condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • • Patients with severe atrophic acne scars (as per Goodman and Baron's acne qualitative scar grading scale)
• Exclusion Criteria:
• • Patients with active acne lesions.
• • Patients having a keloid formation tendency.
• • Patients with a history of bleeding disorder or severe anemia.
• • Pregnant or lactating women.
• • Patients received any treatment for scars in the last 6 months.
• • Patients using drugs causing photosensitivity or systemic retinoids in the previous 6 months (for laser group).