Comparison of Neuromuscular Recovery at the Hand and Foot

Launched by CIUSSS DE L'EST DE L'ÎLE DE MONTRÉAL · Jan 31, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how well we can measure muscle recovery after surgery by comparing readings from special devices placed on the hand and foot. Normally, doctors use an accelerometer on the thumb to check muscle function, but sometimes this can give inaccurate results because the arms might be too tight during surgery. The researchers believe that using a similar device on the first toe could provide more accurate information about how well patients recover from a medication called rocuronium, which temporarily relaxes muscles during surgery.

To participate in this study, you should be between 18 and 74 years old, undergoing elective surgery that requires general anesthesia, and able to speak either French or English. You will also need to meet certain health criteria, such as having a body mass index (BMI) under 36 and not having specific medical conditions like kidney issues or neuromuscular diseases. If you join the study, you can expect to have both devices placed on your hand and foot during your surgery, allowing researchers to gather important information about muscle recovery. This trial is currently recruiting participants, and your involvement could help improve how doctors monitor muscle recovery in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • ASA 1-3 patients
• • Elective surgery
• • Undergoing general anesthesia with rocuronium induced NMB
• • BMI \< 36 kg.m-2
• • Age \> 18 years old
• • French or English speaking patient
• Exclusion Criteria:
• • Renal or hepatic dysfunction
• • Obstructive sleep apnea requiring continuous positive airway pressure (CPAP) machine
• • Neuromuscular disease
• • Peripheral arterial disease (suspected, known or investigated)
• • Calcium channel anomalies
• • Hypothermia (\< 35C)
• • Hyper/hypomagnasemia
• • Allergy to any drug used in the study protocol
• • Patient refusal