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Search / Trial NCT06253988

Effect of Probiotics on Periodontitis Stage III Grade C Molar-incisor Pattern

Launched by AL-AZHAR UNIVERSITY · Feb 9, 2024

Trial Information

Current as of May 15, 2025

Completed

Keywords

Periodontitis Agg. Actinomycetemcomitans Jp2 Genotype Pcr Local Delivery Drug Probiotics

ClinConnect Summary

Background data : Periodontitis is a common disease that represents a public health problem. Aggregatibacter actinomycetemcomitans (A. a ) especially the JP2 genotype plays a major role in the pathogenesis of periodontitis. The aim of this study is to evaluate the effect of topically applied probiotics on the management of periodontitis stage III grade C molar-incisor pattern.

Methods: Sixty-five patients having periodontitis stage III grade C molar-incisor pattern. Screening for A. actinomycetemcomians (A.a) and the JP2 genotype was done using conventional polymerase chain reaction (PCR)....

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • patients have periodontitis stage III grade C molar-incisor pattern .
  • Exclusion Criteria:
  • Pregnant or nursing women,
  • smokers,
  • patients received periodontal therapy,
  • systemic antimicrobials or anti-inflammatory drugs in the last six
  • patients with unacceptable oral hygiene

About Al Azhar University

Al-Azhar University, a prestigious institution in Egypt, is dedicated to advancing medical research and education through rigorous clinical trials. With a strong emphasis on ethical standards and scientific integrity, the university aims to contribute to the development of innovative therapies and healthcare solutions. By fostering collaboration among researchers, healthcare professionals, and academic experts, Al-Azhar University positions itself as a leading sponsor in clinical research, committed to improving patient outcomes and enhancing the understanding of various medical conditions.

Locations

Assiut, , Egypt

Patients applied

0 patients applied

Trial Officials

Ibrahim H Ibrahim, Ass.prof.

Principal Investigator

Al-Azhar University

Mohamed A EL-Mokhtar, Prof

Study Director

Assiut University

Mohamed F Edrees, prof.

Principal Investigator

Al-Azhar University

Heba A Hammad, Ass.prof

Study Director

Assiut University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported