PEP Buddy Impact on Breathing, Exercise, and Sleep Quality in COPD Patients

Launched by CAIRO UNIVERSITY · Feb 29, 2024

Keywords

ClinConnect Summary

The PEP Buddy Impact trial is studying a device called the Positive Expiratory Pressure (PEP) Buddy, which aims to help patients with Chronic Obstructive Pulmonary Disease (COPD) breathe better, exercise more, and improve their sleep quality. Many people with COPD struggle with shortness of breath, especially during physical activity or at night. This trial is looking for participants who are between the ages of 55 and 65 and have moderate to severe COPD, as confirmed by a lung scan. Eligible participants should also have a certain level of lung function and a history of smoking.

If you choose to participate, you will use the PEP Buddy in addition to your regular COPD treatments, like inhalers. The device is designed to help you manage your breathing and reduce feelings of breathlessness, which can lead to a better quality of life. It's important to note that some people may not qualify for the study, especially those with very severe COPD or other serious health conditions. This trial is currently recruiting participants, and being part of it could provide you with new tools to help manage your COPD symptoms.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • • All gender COPD patients
• • Age will be 55-65 years.
• • Moderate to severe COPD patients
• • emphysema on CT scan (HU ≥ - 900)
• • Their FEV1 will be less than 80% predicted
• • Class II obesity (BMI of 35 to \< 40)
• • Medically stable
• • greater than 10 pack-year smoking history
• Exclusion Criteria:
• • • Very severe COPD - Lung cancer
• • Lung resection - Lung fibrosis
• • Heart failure - Cognitive disorders that affect the device application
• • Musculoskeletal or neurological disorders that interfere with an exercise program
• • requiring invasive or non-invasive positive pressure ventilation
• • inability to speak in complete sentences due to breathlessness
• • suspected elevated intracranial pressure - hemodynamic instability
• • recent facial, oral, or skull surgery
• • active hemoptysis (more than two tablespoons of frank blood per day)
• • pneumothorax - failure to comply with the research protocol.
• • uncontrolled hypertension, or other concomitant respiratory diseases
• • participate in any research or pulmonary rehabilitation program during the period of this study.
• • imaging changes of lung disease such as occupancy, exudation, and interstitial changes on CT scan