Pepsinogen II and Helicobacter Pylori Test in Gastric Cancer

Launched by SEOUL NATIONAL UNIVERSITY BUNDANG HOSPITAL · Mar 2, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the use of specific blood tests, called pepsinogens and anti-H. pylori antibody tests, to help screen for gastric cancer (a type of stomach cancer). The goal is to see if these tests can be helpful in identifying people who may have gastric cancer, especially during routine health check-ups. The trial is currently active but not recruiting new participants.

To be eligible for the study, participants must be between the ages of 65 and 74 and should have undergone the required blood tests and a procedure called esophagogastroduodenoscopy (which allows doctors to look inside the stomach) at one of the participating hospitals in Seoul. However, people who have had certain recent treatments, previous stomach surgeries, or other specific conditions will not be included. If someone decides to participate, they can expect to help researchers understand more about gastric cancer screening, but it’s important that they agree to be part of the study and not withdraw their consent later.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Who undergoes serum pepsinogens and anti-H. pylori antibody tests, and esophagogastroduodenoscopy during a health-screening examination at Seoul National University Hospital Gangnam center (SNUHGC) or Seoul National University Bundang Hospital (SNUBH)
• Exclusion Criteria:
• • Who do not receive serum pepsinogens or anti-H. pylori antibody studies
• • Who do not receive esophagogastroduodenoscopy within 3 months before or after the date of serum pepsinogens and anti-H. pylori antibody tests
• • Subjects with recent proton-pump inhibitor therapy 1 month prior to enrollment
• • Subjects with prior history of gastrectomy
• • Subjects with upper gastrointestinal neoplasms other than gastric adenoma/adenocarcinoma
• • Subjects who do not agree to participate in the study or withdraw his/her consent

Trial Officials