Comparing the Effectiveness of Papain Based Chemico-mechanical Caries Removal Gel and 38% Silver Diamine Fluoride for Treating Active Caries Lesion of Primary Molars

Launched by AL-MUSTANSIRIYAH UNIVERSITY · May 8, 2024

Keywords

ClinConnect Summary

This clinical trial is studying two different treatments for cavities in children's teeth, specifically in primary molars (the back teeth that children use for chewing). The researchers want to see how effective a gel containing papain (which helps remove decay) compares to a well-known treatment called silver diamine fluoride (SDF). They will also look at how long each treatment takes, whether any side effects occur, and how anxious the children feel during the treatment.

To participate in the trial, children aged 7 to 8 years old must have cavities in their primary molars that are not too deep and do not touch the nerve of the tooth. Children will not be included if they have allergies to the study treatments or other health concerns. While the trial is currently active, no new participants are being recruited. Parents can expect their children to receive one of the two treatments and to be monitored for any reactions or feelings of anxiety during the process.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Each child should have primary molars with open carious lesions, either on the occlusal surface or Proximal one with the absence of a neighboring tooth.
• • These lesions should affect the dentin but not expose the pulp.
• • The depth of the cavities should measure between 40-99 using a DIAGNOdent caries detection instrument for standardization
• Exclusion Criteria:
• • Children were excluded if parents were unwilling to be assigned to any of the approaches
• • Children that had any abnormal medical condition or silver or papain allergy
• • Chose molars with clinical or radiographic signals of pulp involvement