The Effect of Postbiotics Supplementation on Exercise-induced Oxidative Stress.

Launched by UNIVERSITY OF THESSALY · May 11, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how a supplement called postbiotics might help reduce oxidative stress and improve performance during intense exercise. Oxidative stress refers to damage in the body caused by exercise, and the researchers want to see if taking postbiotics can help with this. The trial involves two groups of participants who will either take the postbiotics supplement or a placebo (a non-active version) for four weeks. They will perform a treadmill exercise and undergo various tests to measure muscle damage and performance both before and after the exercise.

To be eligible for this trial, participants should be physically active and meet certain health criteria, such as having no recent injuries and not taking specific supplements or medications. Participants can expect to be involved in two rounds of exercise testing, separated by a break, where they will complete the same tests under both conditions (postbiotics and placebo). This study aims to provide valuable insights for athletes and coaches about whether postbiotics can effectively support recovery and performance after strenuous workouts.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Physically active subjects (VO2max ≥35ml/kg/min)
• • Absence of musculoskeletal injury (≥6 months)
• • Abstinence from the use of ergogenic supplements (≥1 month)
• • Abstinence from anti-inflammatory drugs (≥1 month)
• • Abstinence from pre-pro-postbiotic supplements (≥6 months)
• • Abstinence from participating in exercise with eccentric content for at least 7 days before exercise
• • Abstinence from alcohol and energy drinks before exercise
• Exclusion Criteria:
• • Recent history of musculoskeletal injury (\<6 months)
• • Use of ergogenic performance supplements (\<1 month)
• • Taking anti-inflammatory drugs (\<1 month)
• • Taking pre-pro-postbiotic supplements (\<6 months)
• • Participation in exercise with eccentric content in the previous 7 days before exercise
• • Consumption of alcohol and energy drinks before exercise