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Search / Trial NCT06513000

Dryness Difference Between Before and After Phacoemulsification

Launched by SOHAG UNIVERSITY · Jul 18, 2024

Trial Information

Current as of May 08, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is looking at how cataract surgery, specifically a procedure called phacoemulsification, affects tear production and eye dryness in patients. The goal is to understand the difference in tear film and its secretion before and after the surgery. Researchers want to see if the surgery helps improve dry eye symptoms for those who have cataracts.

To participate in this study, you need to be over 45 years old and have cataracts. However, people with certain eye problems, those taking specific medications that might affect tear production, or individuals with certain health conditions like diabetes or high blood pressure are not eligible. If you join the trial, you can expect to undergo tests to measure your tear production both before and after the surgery. This study is currently recruiting participants, and anyone interested should consider the eligibility criteria carefully.

Gender

ALL

Eligibility criteria

  • Inclusion criteria:
  • Cataract patients.
  • Cases within age \> 45 years old.
  • Exclusion criteria:
  • Patients with ocular surface diseases and eyelid abnormality.
  • Patients receive ocular or systemic medications, that interfere with tear film production and stability (e.g. topical eye drops that contain preservatives, antihistaminic drugs, anticholinergic drugs, contraceptive pills).
  • Patients with systemic diseases like diabetes, HTN, rheumatoid arthritis. - Patients underwent previous ocular surgeries that interfere with tears instability or production (e.g. refractive surgery, keratoplasty, eyelid surgeries, pterygium excision).
  • Patients with a history of trauma, chemical burn, overusing contact lens (due to damaging the conjunctiva and the goblet cells, also corneal sensitivity reduction).

About Sohag University

Sohag University is a distinguished academic institution located in Sohag, Egypt, committed to advancing healthcare through rigorous clinical research. As a clinical trial sponsor, the university leverages its robust infrastructure and multidisciplinary expertise to facilitate innovative studies aimed at improving patient outcomes and contributing to the global body of medical knowledge. With a focus on ethical standards and scientific integrity, Sohag University collaborates with healthcare professionals and researchers to conduct trials that address critical health issues, ensuring the advancement of evidence-based practices in the healthcare community.

Locations

Sohag, , Egypt

Patients applied

0 patients applied

Trial Officials

Hatem Gamal eldeen, Professor

Study Director

Sohag University

Mahmoud Mohamed farouk, Professor

Study Chair

Sohag University

Hany Mahmoud, Lecturer

Study Chair

Sohag University

Mohamed samir zayed, resident

Principal Investigator

Tahta ophthalmology hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported