Clinical Comparison of Alb-PRF Vs PRF on Postoperative Morbidity Following FGG Harvesting

Launched by CAIRO UNIVERSITY · Aug 21, 2024

Keywords

ClinConnect Summary

This clinical trial is designed to compare two different types of treatments—Albumin Platelet Rich Fibrin (Alb-PRF) and regular Platelet Rich Fibrin (PRF)—to see which one helps reduce complications after a procedure called free gingival graft harvesting. This procedure is often necessary for patients who need gum tissue for dental reasons. The study will take place at Cairo University in Egypt and will involve 39 adult volunteers who are generally healthy and need this type of gum treatment.

If you participate in the trial, you'll first have some photos taken of your mouth, and then you'll be randomly placed in one of three groups: one group will receive Alb-PRF, another will get PRF, and the last group will receive a gelatin sponge. Throughout the study, you will be monitored for 28 days after the procedure, during which you'll follow specific care instructions, take some pain relief if needed, and attend follow-up appointments to check on your healing. To be eligible, you must be over 18, not smoke, and have good oral hygiene. This trial aims to find the best way to support recovery after gum surgery, so your participation could help improve future treatments for others.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients in need of free gingival graft
• • 2. Medically free patients
• • 3. Adult patients above 18 years old.
• • 4. Patients accepting a 1-month follow-up period (cooperative patients).
• • 5. Patients who will provide an informed consent.
• Exclusion Criteria:
• • 1. Smokers
• • 2. Pregnant and lactating women
• • 3. Patients with poor oral hygiene
• • 4. Patients who had previous periodontal surgery in the area of interest