Search / Trial NCT06611618

Analysis of the Loss of Muscle Force, Muscle Power and Motor Control Degradation to Predict the Risk of Falls in Patients With Knee Osteoarthritis

Launched by ISTITUTO ORTOPEDICO RIZZOLI · Sep 20, 2024

Trial Information

Current as of October 03, 2024

Not yet recruiting

Keywords

Falls Prevention Knee Osteoarthritis Muscle Power Muscle Force Motor Control Degradation Digital Twins Imu Mobility Monitoring Mri

Description

Falls are a critical yet common event among the elderly, with huge societal and economic impact (reduced quality of life and high costs for the healthcare system). Experimental measures to quantify the residual muscle strength and power may provide useful information to predict the risk of falls in the elderly. Isometric and isokinetic muscle contractions, performed on a dynamometer or during functional tasks can be collected, together with electromyography (to assess muscle activity) and imaging data (to quantify and characterize muscular tissue). Such data can be collected at different t...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • * Age between 65 and 80 years
  • * Kellgren score II e III
  • * No history of falls in the last 12 months
  • Exclusion Criteria:
  • * Any musculoskeletal, neurological, rheumatic or tumoral diseases
  • * Dementia
  • * Diabetes
  • * Inguinal or abdominal hernia
  • * Severe Hypertension (Level 3)
  • * Severe Cardio-pulmonary insufficiency
  • * Diagnosis of Osteonecrosis in the lower limb joints
  • * Pathologies or physical conditions incompatible with the use of magnetic resonance imaging and electrostimulation (i.e., active and passive implanted biomedical devices, epilepsy, severe venous insufficiency in the lower limbs)
  • * Previous interventions or traumas to the joints of the lower limb

About Sponsor

The National Institute of Allergy and Infectious Diseases (NIAID, /ˈnaɪ.æd/) is one of the 27 institutes and centers that make up the National Institutes of Health (NIH), an agency of the United States Department of Health and Human Services (HHS). NIAID's mission is to conduct basic and applied research to better understand, treat, and prevent infectious, immunologic, and allergic diseases.

Contacts

JC

Jennifer Cobb

Immunology at National Institute of Allergy and Infectious Diseases (NIAID)

Locations

Bologna, , Italy

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0