Analysis of the Loss of Muscle Force, Muscle Power and Motor Control Degradation to Predict the Risk of Falls in Patients With Knee Osteoarthritis
Launched by ISTITUTO ORTOPEDICO RIZZOLI · Sep 20, 2024
Trial Information
Current as of April 02, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how the strength and control of muscles in the legs affect the risk of falling in older adults with knee osteoarthritis (OA). Researchers want to find out if problems with muscle power and motor control are better indicators of falls than just measuring muscle strength. The goal is to create a better way to assess muscle abilities in older patients, helping to prevent falls and improve their safety.
To participate in this study, you need to be between 65 and 80 years old, have a specific type of knee OA, and not have fallen in the past year. During the trial, participants will undergo various assessments, including tests to measure muscle strength and power, monitoring how well they move at home, and having MRI scans of their legs. This is an exciting opportunity for eligible individuals to contribute to important research aimed at improving fall prevention strategies for older adults.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Age between 65 and 80 years
- • Kellgren score II e III
- • No history of falls in the last 12 months
- Exclusion Criteria:
- • Any musculoskeletal, neurological, rheumatic or tumoral diseases
- • Dementia
- • Diabetes
- • Inguinal or abdominal hernia
- • Severe Hypertension (Level 3)
- • Severe Cardio-pulmonary insufficiency
- • Diagnosis of Osteonecrosis in the lower limb joints
- • Pathologies or physical conditions incompatible with the use of magnetic resonance imaging and electrostimulation (i.e., active and passive implanted biomedical devices, epilepsy, severe venous insufficiency in the lower limbs)
- • Previous interventions or traumas to the joints of the lower limb
About Istituto Ortopedico Rizzoli
Istituto Ortopedico Rizzoli is a renowned orthopedic research and treatment institute based in Bologna, Italy, dedicated to advancing musculoskeletal health through innovative clinical trials and cutting-edge medical practices. With a strong emphasis on research, the institute collaborates with leading experts in orthopedics, rehabilitation, and related fields to develop and evaluate new therapies and surgical techniques. Committed to improving patient outcomes, Istituto Ortopedico Rizzoli not only focuses on high-quality clinical care but also fosters a robust research environment that supports the translation of scientific findings into clinical applications.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Bologna, , Italy
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported