An Observational Cohort Study to Explore the Clinical Outcome of Congenital Strabismmus Based on Etiology and Timing of Surgery

Launched by QIYU BO · Sep 24, 2024

Keywords

ClinConnect Summary

This clinical trial is studying congenital esotropia, a condition where a child’s eyes turn inward, which can affect their vision and development. The researchers want to understand the causes of this condition by looking at the genetic factors and clinical characteristics of children with congenital strabismus, as well as their families. They hope this information will help in providing personalized treatment options, especially for those children who undergo surgery to improve their vision.

To participate in this study, children aged between 0 and 36 months who have been diagnosed with congenital esotropia and have had surgery may be eligible. Their guardians need to give consent for them to join the study. However, children with certain conditions that affect vision or those with specific anatomical issues will not be included. Participants will have their genetic information and eye characteristics analyzed, which could lead to a better understanding of their condition and support their development as they grow.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1) Children diagnosed with congenital esotropia and treated with surgery, regardless of gender; 2) Children aged 0-36 months; 3) The guardian of the patient voluntarily signs the informed consent.
• Exclusion Criteria:
• • 1) Esotropia found within 6 months of age due to anatomical abnormalities, extraocular muscle fibrosis, or paralysis or absence of nerves innervating the extraocular muscle; 2) There are diseases or structural abnormalities affecting ocular vision development, such as congenital cataract, congenital microeyeball, congenital glaucoma, genetic or blinding eye diseases with clear genetic mutations, such as Lerber amaurosis and ocular albinism; 3) Those deemed unsuitable for inclusion by the researchers.