FiO2 Delivered with Neonatal BCPAP

Launched by KAROLINSKA INSTITUTET · Sep 24, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how accurately a special type of breathing support called bubble CPAP delivers oxygen to premature infants who have respiratory distress syndrome (RDS). RDS is a common condition in preterm babies that affects their ability to breathe. The researchers want to see if the machines used to provide this support, which mix air and oxygen, are delivering the right amount of oxygen that doctors need to make important decisions about treatment.

To participate, infants must be at least 28 weeks old, be able to breathe on their own, and be receiving bubble CPAP with extra oxygen at the Phu San Hanoi Hospital Neonatology Unit. However, infants who are very unstable or have major health issues, like serious heart defects or recent surgeries, will not be included in the study. Families of participating infants can expect close monitoring while the researchers check how well the bubble CPAP machines are working. This study is important because it could help improve the care provided to premature babies who need breathing support.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Admitted to Phu San Hanoi Hospital Neonatology Unit
• • Bubble CPAP support with added O2
• • ≥28 weeks GA
• • Stable spontaneous breathing
• • Investigation team available
• Exclusion Criteria:
• • Unstable infants in need of urgent intervention
• • Major congenital malformation
• • Known syndrome or neuromuscular disorder
• • Circulatory instability with inotropes
• • Recently extubated (\<24 h)
• • Recent large surgical procedure (\<5 days)