Short-Term Outcome of Medical Vs. Surgical Management Of Chronic Anal Fissure

Launched by SUEZ CANAL UNIVERSITY · Sep 25, 2024

Keywords

ClinConnect Summary

This clinical trial is studying different treatments for chronic anal fissures (CAF), which are painful tears in the lining of the anus that can make it hard to go to the bathroom. The researchers want to compare the effectiveness and safety of a topical medication called Sucralfate (Emoflon®), a combination of two natural substances (azadirachtin and hyperforin, known as HyperOil®), and a traditional surgical option called lateral sphincterotomy. The goal is to find out which treatment works best for healing these fissures.

To be eligible for the trial, participants need to be at least 18 years old and experiencing a chronic anal fissure for the first time. They should be in good overall health (classified as ASA I or II, which means low risk) and not have any serious health issues like sepsis, previous pelvic radiation, or certain cancers. If you join the study, you will be closely monitored to see how well the different treatments work and if they have any side effects. This is an important step towards finding better and more standardized ways to treat chronic anal fissures.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • above 18 years old.
• • CAFs for the first time
• • ASA I, II
• Exclusion Criteria:
• • Sepsis
• • Previous pelvic radiation.
• • recurrent chronic anal fissure
• • Pregnancy or lactation.
• • Immunosuppressive state
• • Malignancy
• • Refusal to participate