Short-Term Outcome of Medical Vs. Surgical Management Of Chronic Anal Fissure
Launched by SUEZ CANAL UNIVERSITY · Sep 25, 2024
Trial Information
Current as of May 19, 2025
Completed
Keywords
ClinConnect Summary
This clinical trial is studying different treatments for chronic anal fissures (CAF), which are painful tears in the lining of the anus that can make it hard to go to the bathroom. The researchers want to compare the effectiveness and safety of a topical medication called Sucralfate (Emoflon®), a combination of two natural substances (azadirachtin and hyperforin, known as HyperOil®), and a traditional surgical option called lateral sphincterotomy. The goal is to find out which treatment works best for healing these fissures.
To be eligible for the trial, participants need to be at least 18 years old and experiencing a chronic anal fissure for the first time. They should be in good overall health (classified as ASA I or II, which means low risk) and not have any serious health issues like sepsis, previous pelvic radiation, or certain cancers. If you join the study, you will be closely monitored to see how well the different treatments work and if they have any side effects. This is an important step towards finding better and more standardized ways to treat chronic anal fissures.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • above 18 years old.
- • CAFs for the first time
- • ASA I, II
- Exclusion Criteria:
- • Sepsis
- • Previous pelvic radiation.
- • recurrent chronic anal fissure
- • Pregnancy or lactation.
- • Immunosuppressive state
- • Malignancy
- • Refusal to participate
About Suez Canal University
Suez Canal University is a distinguished academic institution dedicated to advancing medical research and education in the region. As a clinical trial sponsor, the university focuses on conducting innovative studies that aim to enhance patient care and outcomes. Leveraging its strong network of healthcare professionals and state-of-the-art facilities, Suez Canal University fosters collaboration between researchers and clinicians to explore new therapeutic approaches and validate clinical practices. Committed to ethical standards and scientific rigor, the university plays a pivotal role in contributing to the global body of medical knowledge and improving healthcare delivery.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Ismailia, , Egypt
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported