Native Alignment in the Setting of an Arthritic Knee in Total Knee Arthroplasty

Launched by UNIVERSITY OF LOUISVILLE · Sep 25, 2024

Keywords

ClinConnect Summary

This clinical trial is examining a new way to align implants during total knee replacement surgery for patients with osteoarthritis of the knee. The aim is to see if using the alignment of the healthy knee (the side without arthritis) leads to better results compared to the traditional method, which uses the alignment of the arthritic knee. Researchers will compare two groups of patients: one group will have their implant aligned based on the healthy knee, and the other will follow the usual method. They will look at how well patients recover, their knee function, and their overall satisfaction after the surgery.

To be eligible for this study, participants should be between 21 and 89 years old, need a knee replacement due to osteoarthritis, and have a healthy knee on the opposite side. Those interested will undergo some imaging tests before surgery and will have follow-up appointments at two weeks, six weeks, and one year after the operation. During these visits, they will also fill out questionnaires about their recovery and knee function. This study is currently recruiting participants and aims to gather important information to improve knee replacement outcomes for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patient age is 21-89 at time of surgery
• • 2. Patient is indicated to undergo a unilateral primary TKA, secondary to osteoarthritis
• • 3. Patient's contralateral knee is non-arthritic
• • 4. Patient agrees to participate as a study subject and signs the Informed Consent and Research Authorization document
• • 5. Patient is able to read and speak English.
• Exclusion Criteria:
• • 1. Patient is under the age of 21
• • 2. Patient's primary diagnosis is not osteoarthritis
• • 3. Patient is unable to read and speak English
• • 4. History of previous DVT/PE
• • 5. History of stroke, CABG, or A fib
• • 6. Current smoker