Immunotherapy in Eyelid Viral Papilloma
Launched by ZAGAZIG UNIVERSITY · Dec 5, 2024
Trial Information
Current as of May 20, 2025
Active, not recruiting
Keywords
ClinConnect Summary
This clinical trial is investigating a new treatment for eyelid viral warts, also known as papillomas, using a method called immunotherapy. Instead of traditional surgical options that may be more damaging to the surrounding skin, this study is testing an injection of Candida antigens directly into the warts. The hope is that this approach will be less invasive and help patients recover more comfortably.
To participate in this trial, candidates must be at least 12 years old and have visible eyelid warts, whether just one or several, without any ongoing treatments for the warts. It's important that participants do not have certain conditions, such as pregnancy, breastfeeding, or weakened immune systems, and they should not have had any treatment for warts in the month leading up to the study. Those who join can expect to receive the injection and will be monitored for how well it works and any side effects. This trial is currently active, meaning they are still collecting data, but they are not looking for new participants at this time.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • patients with cutaneous eyelid viral warts whether single or multiple, with no concurrent systemic or topical treatment for warts. Patients aged more than 12 years, with sensitivity test, showed induration less than or equal to five mm. and patients can understand and comply with the requirements of the trials.
- Exclusion Criteria:
- • pregnancy, breastfeeding, patients with immunodeficiency; like diabetics. In addition, patients with a history of hypersensitivity to any used component in this trial, asthma, or allergic skin diseases. Moreover, patients on any treatment modality for warts at least 1 month before the start of the study.
About Zagazig University
Zagazig University, a prominent educational and research institution located in Egypt, plays a pivotal role in advancing medical knowledge and promoting health innovations through its clinical trials. With a commitment to excellence in research, the university leverages its diverse expertise and state-of-the-art facilities to conduct rigorous clinical studies that aim to improve patient care and outcomes. By fostering collaboration among multidisciplinary teams, Zagazig University contributes significantly to the global medical community, ensuring that its clinical trials adhere to the highest ethical standards and regulatory requirements.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Zagazig, , Egypt
Patients applied
Trial Officials
Ayman Marie, Professor
Principal Investigator
Professor of Medical Microbiology and Immunology, Faculty of Medicine, Zagazig University, Egypt
Ghada Boghdadi, Professor
Study Chair
Professor of Medical Microbiology and Immunology, Faculty of Medicine, Zagazig University, Egypt
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported