The Feasibility of Multispectral Optoacoustic Tomography in Different Diseases

Launched by UNIVERSITY MEDICAL CENTER GRONINGEN · Dec 13, 2024

Keywords

ClinConnect Summary

Optoacoustic imaging is a novel imaging method that is based on the optoacoustic effect, first described by Alexander Graham Bell in 1880. When biological tissue is illuminated with an ultrashort laser pulse, tissue chromophores absorb laser light and form pressure transient waves as a result of thermoelastic expansion. These optoacoustic or photoacoustic waves can be detected by wideband ultrasonic transducers around the tissue. Optoacoustic imaging is unique as it resolves optical contrast, but the resolution obeys the rules of ultrasonic diffraction; scattering of the ultrasonic signal i...

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Eligibility criteria

• Inclusion Criteria:
• * Patients with the following diseases will be included:
• • 1. Morbus Sjögren,
• • 2. A superficially located malignant tumor \< 5 centimeter beneath the skin
• • 3. (Peripheral) arterial disease
• • Age ≥ 18 years;
• Exclusion Criteria:
• • Patients with disease localizations or manifestations that do not enable good coupling between the optoacoustic probe and the skin, as decided by the researchers;
• • Medical or psychiatric conditions that compromise the patient's ability to give informed consent.
• • Pregnant women. Women of childbearing potential need to undergo a pregnancy test before participation.