Top Set and Parkinson's Disease
Launched by UNIVERSITY OF MIAMI · Jan 24, 2025
Trial Information
Current as of May 13, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how different types of exercise can help improve power, which is important for daily activities, memory, and decision-making in adults with Parkinson's disease. The researchers want to compare two exercise methods: traditional power training, where participants do exercises as quickly as they can, and a new approach called top set resistance training. In the top set method, participants first do warm-up exercises with gradually increasing weights until they reach a level that is 90% of their maximum strength, before doing the power exercises. If the top set method proves to be more effective, it could help people with Parkinson's disease maintain their independence better than current exercise methods.
To participate in this study, individuals must be between 30 and 90 years old and have a confirmed diagnosis of Parkinson's disease. They should also have a specific score (Hoehn and Yahr score of ≤3) that indicates their level of disease severity, which their doctor can provide. Unfortunately, people with certain health issues, such as uncontrolled heart disease or other serious conditions, or those who are pregnant, cannot join the study. Participants can expect to engage in exercise sessions designed to improve their strength and power, contributing to their overall well-being. This trial is currently looking for volunteers, and all genders are welcome to participate.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Confirmed diagnosis of Parkinson's disease
- • Between the ages of 30-90 years of age
- • A Hoehn and Yahr score of ≤3, which will be provided by the participant's medical provider within 1 year of the study's inception.
- Exclusion Criteria:
- • Uncontrolled cardiovascular disease that prevents participation in a training program
- • Documented HIV infection or another immunodeficiency syndrome
- • Other neuromuscular diseases besides Parkinson's disease
- • Current musculoskeletal injury that prevents exercise.
- • Having a pacemaker
- • Pregnancy
- • Incarcerated individuals
- • Montreal Cognitive Assessment Score below 18
About University Of Miami
The University of Miami, a leading academic institution, is dedicated to advancing medical research and improving patient care through innovative clinical trials. With a commitment to excellence in education and research, the university fosters collaboration among multidisciplinary teams to explore new therapies and treatment modalities. Its extensive clinical programs are supported by state-of-the-art facilities and a diverse patient population, enabling the exploration of cutting-edge solutions to complex health challenges. The University of Miami is poised to contribute significantly to the field of medicine through its rigorous scientific inquiry and a steadfast commitment to ethical research practices.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Coral Gables, Florida, United States
Patients applied
Trial Officials
Joseph F. Signorile, PhD
Principal Investigator
University of Miami
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported