The Effect of Atorvastatin 80 Mg on Hs-CRP/Albumin Ratio in Reducing Thrombus Burden in PCI-STEMI Patients

Launched by UNIVERSITAS SEBELAS MARET · Mar 6, 2025

Keywords

ClinConnect Summary

This study encompasses 40 STEMI patients who underwent primary PCI at Dr. Moewardi General Hospital in Central Java, Indonesia, between September and October. This study employed an experimental design with a pre-and-post technique, with participants recruited through sequential sampling. Patients were subsequently allocated into two groups via a double-blind randomization method. A treatment group was administered a loading dose of high-intensity statin (80 mg atorvastatin) upon initial presentation at the emergency department (ED), whereas the control group received no such intervention. ...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • STEMI with onset less than 24 hour and undergo a Primary PCI
• Exclusion Criteria:
• • STEMI beyond 24 hours from the onset of chest pain
• • Prior statin therapy within the preceding 24 hours
• • Hypersensitivity to statins, pregnancy, lactation, severe inflammatory conditions including active liver dysfunction, chronic kidney disease (eGFR \<30 mL/min), autoimmune disorders, malignancy, severe malnutrition, and
• • Contraindications to statin administration.