Compression Stockings for Lymphedema Prevention in Gynecologic Cancer Patients
Launched by JOANNA KURPIEWSKA-PIENIĄŻEK · Mar 11, 2025
Trial Information
Current as of April 23, 2025
Completed
Keywords
ClinConnect Summary
Background and Rationale Lymphedema is a frequent and debilitating complication following radical surgery for gynecological malignancies. It affects patients' quality of life, contributing to discomfort, impaired mobility, and an increased risk of infections. Despite the widespread use of compression therapy in managing lymphedema, there is limited evidence on its preventive role when applied immediately after surgery.
This study investigates the effectiveness of compression stockings (23-32 mmHg) in reducing the incidence of postoperative lower limb lymphedema and associated symptoms in w...
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • Women who underwent radical surgery for vulvar cancer. Women who underwent radical surgery for cervical, uterine, or ovarian cancer, with systemic pelvic lymph node dissection.
- • Overweight or obese patients (BMI \> 25.0 kg/m²) treated for uterine or ovarian cancer, regardless of whether systemic pelvic lymph node dissection was performed.
- • Women over 18 years of age.
- Exclusion Criteria:
- • Women with a history of lymphedema, venous edema, an ECOG score \> 2, congestive heart failure, renal failure, hypothyroidism, leg ulcers, or severe lower limb ischemia (Fontaine class ≥ 2), as well as those with metastases, relapse, or other malignancies treated within five years prior to study entry, were excluded.
Trial Officials
Joanna Kurpiewska-Pieniążek, PhD
Principal Investigator
Andrzej Frycz Modrzewski Krakow University, Krakow, Poland
About Joanna Kurpiewska Pieniążek
Joanna Kurpiewska-Pieniążek is a dedicated clinical trial sponsor with a strong commitment to advancing medical research and improving patient outcomes. With extensive experience in clinical development and regulatory affairs, she leads initiatives that focus on innovative therapeutic solutions across various therapeutic areas. Her collaborative approach fosters partnerships with research institutions and healthcare professionals, ensuring rigorous adherence to ethical standards and regulatory compliance. Through her leadership, Joanna is committed to enhancing the efficiency and integrity of clinical trials, ultimately contributing to the advancement of healthcare.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Krakow, Lesser Poland Voivodeship, Poland
Krakow, Lesser Poland Voivodeship, Poland
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported