The Correlation Between CT and MRCP Before Living Liver Donation for Liver Blood Vessel Assessment: an Ambidirectional Cohort Study
Launched by ERASMUS MEDICAL CENTER · Mar 10, 2025
Trial Information
Current as of May 09, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
Research methods:
Data, CT-and MRCP images will be extracted from HiX. Screenshots of the images will be made. All personal data will be blacked out using Microsoft Powerpoint 16.90.2. The CT- and MRCP-images will be coded at random with different codes for the CT and MRCP of the same donor. These coded images will be shared with the radiologist through Castor. He will count the blood vessels and look for focal liver lesions. He will register his findings in Castor and share this file with the study coordinator.
Analysis:
Normality will be tested using the Shapiro-Wilk test. Homogeneity ...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- In order to be eligible to participate in this study, a subject must meet all of the following criteria:
- • Living liver donation between May 2004 and June 2026
- • Written informed consent
- In order to be eligible for LDLT, a subject needed to meet all of the following criteria:
- • 18-60 years old
- • Physical and mental well-being
- • Body Mass Index (BMI) \<33 kg/m2
- • No active drugs or other substances use
- Exclusion Criteria:
- • There are no exclusion criteria for this study.
- Exclusion criteria for LDLT were:
- • Absolute exclusion criteria
- • Medical conditions (for instance heart disease and bleeding or clotting disorders)
- • History of liver disease
- • Previous/active malaria infection
- • Financial incentive or indications of pressure
- • Unable to cooperate with designated long-term follow-up
- • Severe psychiatric disease or psychological instability
- • Active alcoholism or frequent heavy alcohol use or drugs use/abuse
- • Unable to give informed consent
- • History of dementia or other neurological degenerative disorders
- • Persons with rabies or persons bitten in the past 6 months by an animal and that are treated as if the animal is rabid
- • Persons with syphilis
- • Human immunodeficiency virus-positive persons. Relative exclusion criteria
- • BMI \>33 kg/m2
- • Smoking
About Erasmus Medical Center
Erasmus Medical Center, located in Rotterdam, Netherlands, is a leading academic medical center renowned for its commitment to advancing healthcare through innovative research and clinical trials. As a prominent institution within the Erasmus University Rotterdam, the center integrates cutting-edge scientific inquiry with comprehensive patient care, focusing on a wide range of medical specialties. With a strong emphasis on multidisciplinary collaboration, Erasmus Medical Center aims to translate research findings into tangible clinical applications, enhancing treatment options and improving patient outcomes. The institution is dedicated to conducting ethical and rigorous clinical trials that contribute to the global body of medical knowledge and foster advancements in personalized medicine.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Rotterdam, South Holland, Netherlands
Patients applied
Trial Officials
Robert C. Minnee, MD, PhD
Principal Investigator
Erasmus Medical Center
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported