EVALUATION of GINGIVAL CREVICULAR FLUID and SERUM ASPROSIN LEVELS in OBESE and NORMAL-WEIGHT INDIVIDUALS with PERIODONTITIS
Launched by GAZI UNIVERSITY · Mar 11, 2025
Trial Information
Current as of May 12, 2025
Completed
Keywords
ClinConnect Summary
No description provided
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. Willingness to participate in the study.
- 2. Weight classification:
- • Obese individuals: Body mass index (BMI) of 30 kg/m² or higher.
- • Normal-weight individuals: BMI between 18.5 and 24.9 kg/m².
- 3. Periodontal health status:
- • Bleeding on probing: less than 10%.
- • Periodontal pocket depth: less than 3 mm.
- • No sites showing attachment loss or alveolar bone loss on radiographs.
- 4. For individuals with periodontitis:
- • At least two non-adjacent teeth must show signs of interdental attachment loss.
- • Periodontal pocket depth greater than 3 mm.
- Exclusion Criteria:
- • 1. Individuals who have received periodontal therapy, any oral decontamination treatment, or antibiotics or steroids in the six months prior to the start of the study.
- • 2. Individuals who are pregnant or breastfeeding.
- • 3. Individuals diagnosed with rheumatoid arthritis or lupus erythematosus.
- • 4. Individuals with a medical history of radiation or cancer therapy.
- 5. Patients with diabetes, defined by:
- • Hemoglobin A1c (HbA1c) level greater than 6.5%.
- • Fasting blood glucose (FBG) greater than 126 mg/dL.
- • An abnormal oral glucose tolerance test (OGTT).
- • 6. Smokers.
About Gazi University
Gazi University, a leading research institution based in Ankara, Turkey, is committed to advancing medical knowledge and improving patient care through innovative clinical trials. With a strong emphasis on interdisciplinary collaboration, the university integrates cutting-edge research with clinical practice to explore new therapeutic approaches and enhance existing treatments. Gazi University adheres to the highest ethical standards and regulatory guidelines, ensuring the integrity and safety of its clinical trials. By fostering partnerships with healthcare professionals and academic institutions, Gazi University aims to contribute significantly to the global scientific community and address pressing health challenges.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Ankara, , Turkey
Patients applied
Trial Officials
Aysen Bodur, Professor
Study Director
Gazi University Faculty of Dentistry Department of Periodontology
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported