EVALUATION of GINGIVAL CREVICULAR FLUID and SERUM ASPROSIN LEVELS in OBESE and NORMAL-WEIGHT INDIVIDUALS with PERIODONTITIS

Launched by GAZI UNIVERSITY · Mar 11, 2025

Keywords

ClinConnect Summary

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Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Willingness to participate in the study.
• 2. Weight classification:
• • Obese individuals: Body mass index (BMI) of 30 kg/m² or higher.
• • Normal-weight individuals: BMI between 18.5 and 24.9 kg/m².
• 3. Periodontal health status:
• • Bleeding on probing: less than 10%.
• • Periodontal pocket depth: less than 3 mm.
• • No sites showing attachment loss or alveolar bone loss on radiographs.
• 4. For individuals with periodontitis:
• • At least two non-adjacent teeth must show signs of interdental attachment loss.
• • Periodontal pocket depth greater than 3 mm.
• Exclusion Criteria:
• • 1. Individuals who have received periodontal therapy, any oral decontamination treatment, or antibiotics or steroids in the six months prior to the start of the study.
• • 2. Individuals who are pregnant or breastfeeding.
• • 3. Individuals diagnosed with rheumatoid arthritis or lupus erythematosus.
• • 4. Individuals with a medical history of radiation or cancer therapy.
• 5. Patients with diabetes, defined by:
• • Hemoglobin A1c (HbA1c) level greater than 6.5%.
• • Fasting blood glucose (FBG) greater than 126 mg/dL.
• • An abnormal oral glucose tolerance test (OGTT).
• • 6. Smokers.

Trial Officials