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Search / Trial NCT06879951

EVALUATION of GINGIVAL CREVICULAR FLUID and SERUM ASPROSIN LEVELS in OBESE and NORMAL-WEIGHT INDIVIDUALS with PERIODONTITIS

Launched by GAZI UNIVERSITY · Mar 11, 2025

Trial Information

Current as of April 23, 2025

Completed

Keywords

Periodontitis Obesity Asprosin Chronic Inflammatory Diseases

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. Willingness to participate in the study.
  • 2. Weight classification:
  • Obese individuals: Body mass index (BMI) of 30 kg/m² or higher.
  • Normal-weight individuals: BMI between 18.5 and 24.9 kg/m².
  • 3. Periodontal health status:
  • Bleeding on probing: less than 10%.
  • Periodontal pocket depth: less than 3 mm.
  • No sites showing attachment loss or alveolar bone loss on radiographs.
  • 4. For individuals with periodontitis:
  • At least two non-adjacent teeth must show signs of interdental attachment loss.
  • Periodontal pocket depth greater than 3 mm.
  • Exclusion Criteria:
  • 1. Individuals who have received periodontal therapy, any oral decontamination treatment, or antibiotics or steroids in the six months prior to the start of the study.
  • 2. Individuals who are pregnant or breastfeeding.
  • 3. Individuals diagnosed with rheumatoid arthritis or lupus erythematosus.
  • 4. Individuals with a medical history of radiation or cancer therapy.
  • 5. Patients with diabetes, defined by:
  • Hemoglobin A1c (HbA1c) level greater than 6.5%.
  • Fasting blood glucose (FBG) greater than 126 mg/dL.
  • An abnormal oral glucose tolerance test (OGTT).
  • 6. Smokers.

Trial Officials

Aysen Bodur, Professor

Study Director

Gazi University Faculty of Dentistry Department of Periodontology

About Gazi University

Gazi University, a leading research institution based in Ankara, Turkey, is committed to advancing medical knowledge and improving patient care through innovative clinical trials. With a strong emphasis on interdisciplinary collaboration, the university integrates cutting-edge research with clinical practice to explore new therapeutic approaches and enhance existing treatments. Gazi University adheres to the highest ethical standards and regulatory guidelines, ensuring the integrity and safety of its clinical trials. By fostering partnerships with healthcare professionals and academic institutions, Gazi University aims to contribute significantly to the global scientific community and address pressing health challenges.

Locations

Ankara, , Turkey

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported