Managing Transient Neurologic Episodes in Surgery for Moyamoya Disease

Launched by STANFORD UNIVERSITY · Mar 11, 2025

Keywords

ClinConnect Summary

This clinical trial is focused on understanding a specific issue that some patients with Moyamoya Disease experience after surgery. It aims to find out how often patients have what are called Transient Neurologic Events (TNEs) in the first 30 days after their surgery. TNEs are temporary neurological problems that can occur following surgery. The researchers will look at various factors during the recovery period to see what might cause these episodes and how they can be minimized.

To participate in this study, individuals must be diagnosed with Moyamoya Disease and are scheduled to undergo a specific type of surgery called extracranial-intracranial bypass, which helps improve blood flow to the brain. Anyone aged 3 years and older can join, as long as they do not have certain other health issues like kidney problems or certain heart conditions. Participants can expect to have their recovery monitored closely for a month after surgery, helping doctors learn more about how to support patients during this critical time.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Moyamoya Disease (MMD) patients undergoing direct extracranial-intracranial (ECIC) bypass. Patients above the age of 3 years old are eligible for the study
• Exclusion Criteria:
• • Renal dysfunction, electrolyte disturbances neuromuscular disorders including Myaesthenia Gravis, heart block