Diet and Exercise Solutions to Postprandial Hypotension

Launched by OHIO STATE UNIVERSITY · Mar 12, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at ways to help people with spinal cord injuries who experience a drop in blood pressure after eating, a condition known as postprandial hypotension. The study will explore if following a low glycemic diet—foods that don't spike blood sugar levels—and using lower-body electrical stimulation can help manage this issue. The trial is not yet recruiting participants, but it aims to include individuals aged 18 to 74 who have a spinal cord injury and rely on a wheelchair for mobility.

To participate, individuals must have had their spinal cord injury for over a year and meet certain criteria, such as not having diabetes or a history of specific health issues. If eligible, participants can expect to follow the diet and participate in electrical stimulation sessions, with the hope of improving their condition. It's important to note that individuals who are currently pregnant, have had certain surgeries, or are on specific medications may not qualify for the study.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Spinal cord injury (SCI) between C4 and T12 who require use of wheelchair for daily mobility
• • AIS A or B
• • \>1-year post-injury
• Exclusion Criteria:
• • Currently pregnant of breast-feeding
• • Type 1 or 2 diabetes
• • Previous gut augmentation bariatric surgery
• • Neurological impairment other than SCI
• • History of uncontrolled autonomic dysreflexia
• • History of bone fractures
• • Use of abdominal binder or anti-hypotensive drugs
• • Fitted with pacemaker or defibrillator
• • Currently receiving electrical stimulation training or in the previous year