Effectiveness of Pelvic Floor Muscle Rehabilitation Combined With Desmopressin in Children With Primary Monosymptomatic Nocturnal Enuresis

Launched by BAHÇEŞEHIR UNIVERSITY · Mar 16, 2025

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a special program called Structured Pelvic Floor Muscle Rehabilitation (SPFMR) combined with a medication called desmopressin to help children who wet the bed, a condition known as Primary Monosymptomatic Nocturnal Enuresis (PMNE). The researchers want to see if adding SPFMR can help reduce how often and how severely children experience bedwetting episodes, both in the short term and the long term. Children in the trial will be divided into two groups: one will receive desmopressin and participate in SPFMR sessions, while the other group will only receive desmopressin. Both groups will keep a diary to track their bedwetting episodes and will be checked regularly to see if their condition improves.

To participate in this study, children need to be between 7 and 13 years old and have been diagnosed with PMNE in the last six months. They should not have any urinary tract infections or other significant health issues that could affect the study. Families who are interested must be willing to participate and communicate in Turkish. Throughout the trial, children will learn techniques to help strengthen their pelvic floor muscles, which may help with their bedwetting. This study aims to provide new insights into effective treatments for children who struggle with this common issue.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Being between 7 and 13 years old
• • Diagnosed with primary MNE by a pediatric urology department within the last 6 months
• • No urinary tract infection verified by laboratory tests
• • Ability to communicate in Turkish and absence of mental deficit
• • No diagnosed psychiatric problems
• • Willingness to participate in the study (child and family)
• Exclusion Criteria:
• • Presence of orthopedic conditions preventing evaluation
• • Anatomical anomalies in the urinary system
• • History of urinary system surgery
• • Neurological disorders
• • Presence of mental retardation
• • History of orthopedic surgery that could alter pelvic or lower extremity integrity
• • Receiving PFM rehabilitation in the last 6 months
• • Using nighttime alarm therapy in the last 6 months
• • Receiving any treatment for enuresis in the last 6 months