Educational Programs Based on Healthy Habits to Improve Quality of Life and Psychosocial Profile in Women With Neurodegenerative Diseases: the ADVICE Protocol Study (Phase 2)

Launched by UNIVERSIDAD DE ALMERIA · Mar 13, 2025

Keywords

ClinConnect Summary

This clinical trial, called the ADVICE Protocol Study, is exploring different educational programs designed to help improve the quality of life for people with relapsing-remitting multiple sclerosis (MS). The study will compare two types of in-person programs—one focused on high-intensity interval training (HIIT) and the other on strength training—with a self-guided online program that uses resistance bands. Participants will also learn about the Mediterranean diet and cognitive-behavioral techniques to support their well-being. The study aims to see how these programs affect participants' health and happiness over time, with follow-up evaluations three and six months after the programs.

To join the study, participants need to be between 18 and 45 years old, have stable MS, and be able to walk independently for at least 10 meters. Women will be recruited first, and then men will be matched with them based on age and lifestyle factors. This is an exciting opportunity for individuals with MS to engage in activities that could potentially enhance their lives while also contributing to important research in this area.

Gender

ALL

Eligibility criteria

• Inclusion criteria include:
• • Women and men of reproductive age (18-45 years) with MS will be included, with the upper age limit adjusted to reflect the reproductive phase;
• • no iron-deficiency anemia;
• • stable disease phase;
• • independent walking ability for over 10 meters.
• • Women will be recruited first and later matched with men based on age, EDSS, and lifestyle habits (physical activity, smoking, and alcohol consumption).
• Exclusion criteria will include participants with MS who:
• • score \<1 or \>6 on the EDSS;
• • report a relapse within 12 months before the study begins;
• • have taken corticosteroid treatment within the last 2 months;
• • have participated in a structured training program in the previous 6 months.
• • Once all women with MS are recruited, male participants will be recruited following a 1:1 matching methodology based on age, geographic region, and lifestyle habits.