Effect of Mannitol on Propofol Level
Launched by CUKUROVA UNIVERSITY · Mar 18, 2025
Trial Information
Current as of April 22, 2025
Not yet recruiting
Keywords
ClinConnect Summary
The participants will divide into the two groups. Group 1 will include 20 patients aged 18 years and over, American Society of Anesthesiologist (ASA) II-III class, who will undergo supratentorial tumor surgery, (Mannitol group) and Group 2 will include 20 patients who will undergo pituitary surgery without mannitol (Control Group). Total intravenous anesthesia (TIVA) will be adjusted to propofol 4 µg/dl and remifentanil 2-4 µg/dl with target-controlled infusion pumps. In the mannitol group, 2.5 ml/kg (0.5 g/kg) will be given to all patients 15 minutes after induction and the mannitol infusi...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • American Society of Anesthesiologist (ASA) II participants
- • supratentorial tumor surgery
- • eligible for mannitol use
- • eligible for Total intravenous anesthesia (TIVA)
- Exclusion Criteria:
- • American Society of Anesthesiologist (ASA) III and upper
- • Chronic kidney failure
- • sepsis
- • multiorgan failure
About Cukurova University
Cukurova University, a prominent institution located in Adana, Turkey, is dedicated to advancing medical research and improving healthcare outcomes through innovative clinical trials. With a strong emphasis on interdisciplinary collaboration, the university fosters a dynamic research environment that promotes the development of new therapies and treatment modalities. Its commitment to ethical standards and patient safety ensures that all clinical trials are conducted with the highest level of scientific rigor. Cukurova University aims to contribute significantly to the global medical community by facilitating groundbreaking studies that address pressing health challenges.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported