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Search / Trial NCT06884657

Effect of Mannitol on Propofol Level

Launched by CUKUROVA UNIVERSITY · Mar 18, 2025

Trial Information

Current as of April 22, 2025

Not yet recruiting

Keywords

ClinConnect Summary

The participants will divide into the two groups. Group 1 will include 20 patients aged 18 years and over, American Society of Anesthesiologist (ASA) II-III class, who will undergo supratentorial tumor surgery, (Mannitol group) and Group 2 will include 20 patients who will undergo pituitary surgery without mannitol (Control Group). Total intravenous anesthesia (TIVA) will be adjusted to propofol 4 µg/dl and remifentanil 2-4 µg/dl with target-controlled infusion pumps. In the mannitol group, 2.5 ml/kg (0.5 g/kg) will be given to all patients 15 minutes after induction and the mannitol infusi...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • American Society of Anesthesiologist (ASA) II participants
  • supratentorial tumor surgery
  • eligible for mannitol use
  • eligible for Total intravenous anesthesia (TIVA)
  • Exclusion Criteria:
  • American Society of Anesthesiologist (ASA) III and upper
  • Chronic kidney failure
  • sepsis
  • multiorgan failure

About Cukurova University

Cukurova University, a prominent institution located in Adana, Turkey, is dedicated to advancing medical research and improving healthcare outcomes through innovative clinical trials. With a strong emphasis on interdisciplinary collaboration, the university fosters a dynamic research environment that promotes the development of new therapies and treatment modalities. Its commitment to ethical standards and patient safety ensures that all clinical trials are conducted with the highest level of scientific rigor. Cukurova University aims to contribute significantly to the global medical community by facilitating groundbreaking studies that address pressing health challenges.

Locations

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported