Study of Placental Inflammation in Gestational Diabetes
Launched by FONDAZIONE POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI IRCCS · Mar 18, 2025
Trial Information
Current as of May 09, 2025
Active, not recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how inflammation in the placenta may affect women with gestational diabetes mellitus (GDM), a type of diabetes that occurs during pregnancy. Specifically, the researchers are looking at a protein called NLRP3 and a chemical messenger that helps regulate inflammation. Understanding this could help improve care for women with GDM and their babies.
To be eligible for this study, women must be over 18 years old, have a singleton pregnancy (meaning they are pregnant with one baby), and have been diagnosed with gestational diabetes but have an otherwise uncomplicated pregnancy. Unfortunately, women under 18, those with infections, multiple pregnancies, or a history of cancer cannot participate. While the trial is currently active, it is not recruiting new participants at this time. If eligible women were to join, they would likely undergo tests and monitoring related to their condition, contributing valuable information to enhance understanding of gestational diabetes.
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • Women with gestational diabetes mellitus
- • Women with uncomplicated pregnancy
- • Age \>18 years
- • Singleton pregnancy
- Exclusion Criteria:
- • Age \< 18 years
- • Infections (HIV,HCV)
- • Multiple pregnancy
- • Cancer
About Fondazione Policlinico Universitario Agostino Gemelli Irccs
Fondazione Policlinico Universitario Agostino Gemelli IRCCS is a leading research and healthcare institution based in Rome, Italy, renowned for its commitment to advancing medical science and improving patient care. As a prominent academic medical center affiliated with the Catholic University of the Sacred Heart, it integrates clinical practice, education, and research, fostering innovation in various fields of medicine. The foundation conducts a wide range of clinical trials aimed at developing new therapies and enhancing treatment protocols, with a focus on translational research that bridges the gap between laboratory discoveries and patient care. Its multidisciplinary approach and dedication to high ethical standards position it as a key player in the landscape of clinical research and healthcare improvement in Italy and beyond.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Rome, , Italy
Patients applied
Trial Officials
Chiara Tersigni
Principal Investigator
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported