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Search / Trial NCT06886100

Melanin Recurrence in Scalpel and LASER Gingival Depigmentation in Thin and Thick Phenotypes.

Launched by THAMAR UNIVERSITY · Mar 14, 2025

Trial Information

Current as of April 29, 2025

Completed

Keywords

Depigmentation; Healing; Laser; Melanin; Pain; Phenotype

ClinConnect Summary

Background: Removal of unsightly pigmented gingiva is the need for a pleasant and confident smile. Many studies were done to study the melanin recurrence in both surgical and laser melanin depigmentation. To best of our knowledge, there is no published article regarding comparison of melanin recurrence between both techniques taking in consideration the gingival phenotype. So this study aimed to compare melanin pigmentation recurrence, pain perception and wound healing between laser and scalpel surgeries in thin and thick gingival phenotypes.

Methods: Thirty patients (60 sites) were includ...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • (i) Be aged at least 20 years, (ii) had bilateral physiologic melanin hyperpigmentation of gingiva (dark gums) in the anterior segment with severe grade II melanin hyperpigmentation (according to modification of melanin index categories 1977), (iii) periodontally healthy with good oral hygiene, (iv) had esthetic concern, (v) systemically healthy, (vi) no dental crowding and (vii) those willing to undergo minor surgical procedures.
  • Exclusion Criteria:
  • (i) any systemic disease associated with pathological hyperpigmentation), (ii) non-treated periodontal disease, (iii) chronic smokers, (iv) subjects with a mouth breathing habit (ii) subjects with crown restorations or fillings involving the incisal edge on anterior maxillary teeth, (v) non-compliant patients (vi) missing any of the six maxillary anterior teeth and having Millers Class III or Class IV recession (vii) pregnant or lactating females and (viii) (ix) gingival pigmentation of hemoglobin, melanoid, melanoma and carotene , (x) Gingival pigmentation adjacent to amalgam restoration, and (xi) Long-term usage of antimalarial drugs and minocycline.

About Thamar University

Thamar University is a distinguished academic institution dedicated to advancing health sciences through innovative research and education. As a clinical trial sponsor, Thamar University leverages its robust academic resources and interdisciplinary expertise to conduct rigorous clinical studies aimed at enhancing medical knowledge and improving patient outcomes. Committed to ethical research practices and collaboration with healthcare professionals, the university fosters an environment conducive to scientific discovery and the translation of research findings into clinical applications. Through its clinical trials, Thamar University aims to contribute significantly to the healthcare community and support the development of effective treatments and interventions.

Locations

Sanaa, , Yemen

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported