Comparison of MiSight 1-Day and Acuvue Oasys for Presbyopia in Myopic Children

Launched by PAULINE KANG · Mar 14, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how two different types of contact lenses affect the progression of myopia, commonly known as nearsightedness, in children aged 6 to 12 years. The trial is comparing MiSight 1-Day contact lenses with ACUVUE OASYS for PRESBYOPIA lenses to see which one better helps control the worsening of myopia over a year. Myopia can make it difficult to see things far away, and this study aims to find out which lens option is more effective for managing this condition in young children.

To participate in the study, children must be between 6 and 12 years old, willing to wear contact lenses daily, and have a specific level of nearsightedness. Participants should have good overall health and no history of certain eye conditions or surgeries that could affect lens use. Throughout the trial, participants will wear one of the two types of contact lenses and be monitored for any changes in their vision. This study is currently active but not recruiting new participants, meaning they are not looking for more volunteers at this time.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Aged 6-12 years (inclusive)
• • 2. Is willing to wear soft contact lenses daily
• • 3. Spherical equivalent myopic refractive error between -0.50 to -5.00 D in each eye and astigmatism \< 1.00 D
• • 4. Best corrected logMAR visual acuity of 0.1 or better in both eyes
• • 5. Good ocular and general health
• • 6. No previous use of myopia control interventions for more than 1 month or within the last 30 days
• • 7. Competent enough in English to be able to fully understand the participant information and consent form
• Exclusion Criteria:
• • 1. Strabismus at distance or near, amblyopia or significant anisometropia (\>1D)
• • 2. Systemic or ocular conditions that may affect contact lens use (e.g., allergy) or that may affect refractive development (e.g., ptosis)
• • 3. Previous history of ocular surgery, trauma, or chronic ocular disease
• • 4. Contraindications to contact lens use
• • 5. Ocular or systemic medication use which may interfere or interact with contact lens wear or ocular development
• • 6. Plans to migrate or move during the study
• • 7. Child, parents or guardians not willing to comply with treatment and/or follow-up schedule