Interactive Home-based Rehabilitation Exercise Assessment Platform and Exploration of Clinical Effects in Patients with Parkinson's Disease

Launched by TAIPEI VETERANS GENERAL HOSPITAL, TAIWAN · Mar 17, 2025

Keywords

ClinConnect Summary

This clinical trial is exploring a new way to help people with Parkinson's disease improve their strength and overall health through a program that combines exercise and technology. Researchers are developing a special platform that provides visual feedback, similar to virtual reality, to enhance rehabilitation exercises. In this study, 92 participants with Parkinson's will be divided into three groups: one will receive standard clinical rehabilitation, another will do home-based rehabilitation exercises, and the last group will not receive any specific intervention. Each participant will take part in sessions twice a week for 12 weeks, focusing on both strength and aerobic exercises. They will be evaluated on various measures, including their grip strength, walking ability, and quality of life.

To participate in this trial, individuals must be diagnosed with Parkinson's disease, be between 45 and 85 years old, and be able to walk independently or with assistance. They should also be stable on their medications and have a good understanding of the study requirements. However, those with certain serious health conditions, severe impairments, or who are pregnant or breastfeeding will not be eligible. This trial aims to provide valuable insights into how this interactive exercise program can benefit people living with Parkinson's disease.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients diagnosed with primary Parkinson's disease by a neurologist
• • 2. Modified Hoehn and Yahr Scale I-III
• • 3. Aged 45-85 years old
• • 4. Mini-Mental State Examination (MMSE) score of 24 or above
• • 5. Stable on Parkinson's disease-related medications
• • 6. Able to walk independently or use assistive devices to walk 15 meters
• • 7. Able to understand the movements and test items
• • 8. Able to understand and willing to sign the informed consent form
• Exclusion Criteria:
• • 1. Rheumatic diseases
• • 2. Unstable heart and respiratory diseases (such as angina pectoris, pulmonary embolism, etc.)
• • 3. Severe or unstable neurological or orthopedic diseases (such as stroke, dementia, fractures, etc.)
• • 4. Severe hearing or visual impairment, unable to cooperate with researchers
• • 5. People diagnosed with mental illness
• • 6. People with a history of epilepsy or a direct blood relative with a history of epilepsy
• • 7. Pregnant or breastfeeding women
• • 8. People with any uncontrolled chronic diseases that may cause safety concerns
• • 9. People living without family members or case caregivers.