Single-Dose Hybrid Hyaluronic Acid and Sodium Chondroitin with Rehabilitation for Sports Adults with Knee Osteoarthritis
Launched by UNIVERSITY OF PALERMO · Mar 16, 2025
Trial Information
Current as of April 23, 2025
Not yet recruiting
Keywords
ClinConnect Summary
No description provided
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Adults aged between 18 and 50 years.
- • Radiologically confirmed diagnosis of knee osteoarthritis (Kellgren-Lawrence grade ≤3), present for at least 6 months.
- • Persistent moderate to severe pain due to osteoarthritis, interfering with physical performance.
- • Documented reduction in sports performance (use appropriate scales or tests to validate this).
- • Lack of response to pharmacological or other conservative treatments.
- • Willingness to provide written informed consent for participation.
- Exclusion Criteria:
- • Coexisting rheumatic diseases.
- • History of intra-articular viscosupplementation in the target knee within the previous 6 months.
- • Presence of significant venous or lymphatic stasis.
- • Body Mass Index (BMI) ≥ 30 kg/m².
- • Use of systemic or intra-articular corticosteroids in the target knee within the last 3 months.
- • Chronic use of topical/systemic analgesics, NSAIDs, or narcotics.
- • History of alcohol or drug abuse.
- • Allergy or hypersensitivity to hyaluronic acid or any of its components.
- • Pregnant or breastfeeding women, or those not using adequate contraception.
About University Of Palermo
The University of Palermo, a distinguished institution located in Italy, is dedicated to advancing medical research and education through innovative clinical trials. Renowned for its commitment to scientific excellence, the university leverages its multidisciplinary expertise and state-of-the-art facilities to conduct research that addresses critical healthcare challenges. By fostering collaborations with leading researchers and healthcare professionals, the University of Palermo aims to translate scientific findings into effective therapies, ultimately contributing to improved patient outcomes and public health advancements.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Palermo, Italia, Italy
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported