The Association Mechanism Between the Microbiome and the Development of Community Pneumonia Was Studied Based on the Analysis of Pulmonary Microbiota - Host Interaction Network

Launched by SUN YAT-SEN MEMORIAL HOSPITAL OF SUN YAT-SEN UNIVERSITY · Mar 20, 2025

Keywords

ClinConnect Summary

This clinical trial is exploring how the bacteria and other microorganisms in our lungs (known as the pulmonary microbiome) may affect the development of community-acquired pneumonia (CAP), a type of lung infection that people can get outside of a hospital setting. Researchers are comparing the lung bacteria from healthy individuals to those with CAP to identify specific types of bacteria that may contribute to this illness. They are also looking to understand how these bacteria interact with the body's immune response and the substances (metabolites) they produce, which could help us learn more about pneumonia and how to treat it.

To participate in this study, individuals must meet certain criteria, including having a confirmed diagnosis of community-acquired pneumonia based on established guidelines. It's important to note that the trial is currently active but not recruiting new participants at this time. For those who may have been included, they would undergo tests to analyze their lung bacteria and immune responses, which could help improve our understanding of pneumonia and potentially lead to better treatments in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • According to the CAP clinical diagnostic criteria in the Guidelines for the Diagnosis and Treatment of Community-Acquired Pneumonia in Adults in China (2016 edition), cases eligible for community-acquired pneumonia were included and screened.
• Exclusion Criteria:
• • Alveolar lavage fluid samples without electronic bronchoscopy were excluded for mNGS etiological examination of the case.