Characterization of Immune Cells and Their Secreted Cytokines in Endometriosis Patients

Launched by MEDICAL UNIVERSITY OF LUBLIN · Mar 24, 2025

Keywords

ClinConnect Summary

The EUmetriosis project is a clinical trial focused on understanding endometriosis, a painful condition that affects women. The aim is to improve how this condition is diagnosed and managed. Researchers want to learn more about the immune cells and substances they release in women with endometriosis. This study is important because it seeks to address key challenges faced by those living with the condition, including finding better treatment options and raising awareness about endometriosis. By doing this, the project hopes to make life easier and improve care for women with this condition.

To be eligible for the trial, participants need to be women aged between 18 and 50 who have been diagnosed with endometriosis and are planning to have surgery. They should be pre-menopausal and experience regular menstrual cycles. Participants will be asked to collect some menstrual fluid (effluent) for testing and will need to provide consent to join the study. It’s important to note that women who are post-menopausal, pregnant, or have certain other health conditions will not be eligible. This trial is yet to start recruiting participants, but it aims to provide valuable insights that could lead to better management of endometriosis in the future.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Women with a clinical and/or ultrasound diagnosis of endometriosis who are candidates for surgery
• • Age between 18 and 50 years
• • Pre-menopausal status
• • Experiencing regular menstruation
• • Willing to collect menstrual effluent
• • Signature of informed consent to the study
• Exclusion Criteria:
• • Age below 18 years
• • Post-Menopausal status
• • Presence of Crohn's disease
• • Presence of Ulcerative Colitis
• • Presence of short bowel syndrome or another chronic inflammatory disease
• • Use immunosuppressive medication
• • Receiving contraceptive hormone therapy
• • Pregnant
• • Presence/history of malignancy