Neonatologist-Performed Lung Ultrasound (NPLUS) to Guide Respiratory Therapy

Launched by ROYAL HOSPITAL FOR WOMEN · Mar 23, 2025

Keywords

ClinConnect Summary

NPLUS is used to detect various artifacts that emerge due to air and fluid ratio in the lungs. The image results form a beam reflection and reverberation of echoes on tissues. The most important artifacts display A-lines, B-lines and the pleural line with the lung sliding. A-lines (horizontal, hyperechogenic long line reverberation artefacts of the pleura) are a sign of aeration. B-lines (vertical, hyperechoic ring-down artefacts arising from the pleural line) indicate fluid in the interstitial space. The pleural line is a smooth, hyperechoic line. Breathing or ventilation causes a movement...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • All preterm infants (\<33 weeks gestational age) from their 2nd week of life, receiving respiratory support via NCPAP
• • expected to stay on NCPAP for the following 5 days at the NICU, Royal Hospital for Women, Randwick, Sydney
• • provided written informed consent obtained from parents.
• Exclusion Criteria:
• • Neonates with previous abdominal surgery
• • Major congenital anomalies.
• • \>33+0 weeks
• • Less than 1 week of age
• • Invasive ventilation
• • Bilevel or Multilevel non-invasive ventilation
• • Not expected respiratory support via CPAP for the following 5 days.

Trial Officials