A Low-Carb Approach to Treat Type 2 Diabetes in Pediatric Patients

Launched by UNIVERSITY OF ALABAMA AT BIRMINGHAM · Mar 27, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how a low-carb diet might help adolescents with Type 2 diabetes (T2D) compared to a standard carbohydrate diet. Over a period of 24 weeks, researchers will study the effects of these two diets on young people aged 12 to 18 who have been diagnosed with diabetes for at least three months. To qualify for the trial, participants must have a specific range of blood sugar levels and a higher body weight, while also being on stable doses of certain diabetes medications.

The trial is not yet recruiting participants, but if you or someone you know is interested, it's important to know that those currently using insulin or with certain health issues related to kidney or liver function won't be eligible. Participants can expect regular check-ins and support as they follow the assigned diet, helping researchers understand how diet changes can influence diabetes management in young people. This could be a valuable opportunity to contribute to important research in diabetes care.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age 12-18
• • Diabetes diagnosis \>3 months to ensure stable baseline glycemic control
• • HbA1C between 6.5- 8.5%
• • BMI \>85th percentile
• • Negative pancreatic autoantibodies
• • Stable dose of anti-diabetic drugs GLP-1, metformin, SGLT-2 inhibitors, for 3 months
• Exclusion Criteria:
• • Current insulin treatment
• • Renal impairment measured as creatinine \> 1 mg/dL
• • Hepatic dysfunction measured as AST and ALT \>100 IU/ml