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Search / Trial NCT06903039

NeoRes Study - Preoperative Chemotherapy in Colorectal Peritoneal Disease Prior to Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC)

Launched by UPPSALA UNIVERSITY · Mar 24, 2025

Trial Information

Current as of May 09, 2025

Completed

Keywords

Colorectal Cancer Peritoneal Metastases Systemic Chemotherapy Chemotherapy Sensitivity Testing

ClinConnect Summary

Neores Study: Evaluating Systemic chemotherapy efficacy in colorectal peritoneal metastases

Ansvarig forskare:

Peter Cashin Akademiska sjukhuset / Uppsala universitet

Research plan Background The effectiveness of systemic chemotherapy on peritoneal metastases is still rather poorly investigated. It is clear from randomized medical oncology trials that patients with peritoneal metastases from colorectal cancer do more poorly than other metastatic colorectal cancer. Currently, many countries use neoadjuvant therapy as a downstaging treatment or a test of tumor biology prior to selecting pa...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • HIPEC MDK where extensive isolated peritoneal metastases are noted
  • Colorectal cancer
  • Decision during HIPEC MDT to start systemic conversion chemotherapy
  • Exclusion Criteria:
  • Appendiceal cancer
  • Retroperitoneal lymph node metastases
  • Other systemic metastases (e.g. liver, lung, brain, bone etc)

About Uppsala University

Uppsala University, a prestigious institution located in Sweden, is renowned for its commitment to advancing medical research and education. As a clinical trial sponsor, the university leverages its extensive expertise in various fields of health sciences to conduct innovative studies aimed at improving patient outcomes and understanding complex diseases. With a strong emphasis on ethical standards and rigorous scientific methodologies, Uppsala University collaborates with a network of researchers, healthcare professionals, and industry partners to facilitate groundbreaking clinical trials that contribute to the global body of medical knowledge.

Locations

Uppsala, , Sweden

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported