the Effect of Monk Fruit and Splenda on Salivary Ph and Streptococcus Mutans Count in Vivo Study

Launched by AL-MUSTANSIRIYAH UNIVERSITY · Apr 8, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how two sweeteners, Monk Fruit and Splenda, affect saliva's acidity and the amount of a specific bacteria called Streptococcus mutans, which is linked to tooth decay. Participants will use a mouth rinse made with these sweeteners and then have their saliva tested to see how the rinse changes the saliva’s pH (which indicates acidity) and the count of the bacteria. The study will measure these changes at different times after using the rinse.

To join this study, participants should be healthy individuals aged 20 to 24, with no current tooth decay or oral diseases. They should not have received any recent dental treatments or be taking medications that affect saliva flow. Those who have active cavities or painful oral conditions won’t be eligible. Participants can expect to provide saliva samples before and after using the mouth rinse, and the study is designed to help understand how these sweeteners might influence oral health.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • participants aged (20-24) years.
• • No active carious lesions or oral diseases.
• • Generally healthy individuals without systemic illnesses.
• • No prior use of preventive dental treatments
• Exclusion Criteria:
• • Participants currently undergoing dental treatment.
• • Those taking medications that alter saliva flow.
• • Presence of painful oral conditions or systemic diseases. Participants have active caries