Clinical Trials for Acute Myeloid Leukemia (AML)

Find clinical trials for acute myeloid leukemia (aml). Discover research opportunities and treatment options in your area.

42 Active Trials Found

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Phase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological Malignances

NCT ID: NCT05092451

This clinical trial is exploring a new treatment approach for patients with certain blood cancers, including B-Cell Lymphoma, Myelodysplastic Syndromes (MDS), and Acute Myeloid Leukemia (AML). The ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

A Study of Gilteritinib, Venetoclax and Azacitidine as a Combined Treatment for People Newly Diagnosed With Acute Myeloid Leukemia

NCT ID: NCT05520567

This clinical trial is studying a new combination treatment for people who have just been diagnosed with acute myeloid leukemia (AML), specifically those with a specific change in their FLT3 gene. ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Columbus, Ohio, United States, Boston, Massachusetts, United States +19 more

Registry Study on Patient Characteristics, Biological Disease Profile and Clinical Outcome in Acute Myeloid Leukemia and Related Neoplasms - The Biology and Outcome (BiO)-Project

NCT ID: NCT01252485

The BiO-Project is a clinical trial that aims to understand more about acute myeloid leukemia (AML) and certain related blood disorders, including higher risk myelodysplastic syndromes (MDS). This ...

Recruiting

Type: observational Locations: Hamburg, , Germany, Augsburg, , Germany +90 more

Study on Optimizing the Treatment of Patients With Acute Myeloid Leukemia Based on Early Peripheral Blood Minimal Residual Disease

NCT ID: NCT07023588

This clinical trial is studying a new way to improve treatment for people with acute myeloid leukemia (AML), a type of blood cancer. The researchers want to see if checking for tiny amounts of leuk...

Recruiting

Phase: PHASE2 Type: interventional Locations: Changchun, Jilin, China

Effectiveness of Medium-Dose Cytarabine Combined With Venetoclax for Consolidation Therapy in Elderly Patients With Intermediate to High-Risk Acute Myeloid Leukemia

NCT ID: NCT06990321

This clinical trial is investigating the effectiveness of a treatment combining medium-dose Cytarabine and Venetoclax for elderly patients with a type of blood cancer called Acute Myeloid Leukemia ...

Recruiting

Phase: PHASE3 Type: interventional Locations: Changchun, Jilin, China

uCD7 CART for Relapsed or Refractory CD7 Positive Hematologic Malignancies

NCT ID: NCT07109518

This clinical trial is testing a new treatment called uCD7 CAR-T cell therapy for adults with certain types of blood cancers that have not responded to other treatments or have come back after trea...

Recruiting

Phase: PHASE1 Type: interventional Locations: Tianjin, Tianjin, China

A Study of Azacitidine and Venetoclax in People With Acute Myeloid Leukemia (AML)

NCT ID: NCT06773208

This clinical trial is investigating whether a combination of two medications, azacitidine and venetoclax, can effectively reduce or eliminate measurable residual disease (MRD) in adults with acute...

Recruiting

Phase: PHASE2 Type: interventional Locations: New York, New York, United States, Harrison, New York, United States +5 more

Ex Vivo T-Cell-Depleted Haploidentical Transplantation Bridging With Chimeric Antigen Receptor T-cell Therapy and Prophylactic Memory T Cell Infusion for Acute Leukemia

NCT ID: NCT07087847

This clinical trial is studying a new treatment approach for people with hard-to-treat or returning acute leukemia, a type of blood cancer. After receiving a special type of therapy called CAR-T, w...

Not yet recruiting

Phase: NA Type: interventional Locations: Shanghai, Shanghai, China

Monitoring, Detoxifying, and Rebalancing Metals During Acute Myeloid Leukemia (AML) Therapy, a Phase 2 Randomized Study

NCT ID: NCT06811233

This clinical trial is studying whether a treatment that removes excess metals from the body can improve the results for patients with acute myeloid leukemia (AML) during their standard therapy. Re...

Recruiting

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States

Ivosidenib as Post-HSCT Maintenance for AML

NCT ID: NCT06707493

This clinical trial is studying a medication called ivosidenib, which is being tested as a treatment for patients with a specific type of blood cancer known as acute myeloid leukemia (AML) that has...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Boston, Massachusetts, United States, Boston, Massachusetts, United States

Study of Oral Venetoclax Tablets to Evaluate Adverse Events and Change in Disease Activity in Participants Above 19 Years of Age With Acute Myeloid Leukemia (AML)

NCT ID: NCT04826523

This clinical trial is studying the safety and effectiveness of a medication called oral venetoclax in adults with Acute Myeloid Leukemia (AML), a serious type of cancer affecting white blood cells...

Recruiting

Type: observational Locations: Seoul, , Korea, Republic Of, Seoul, Seoul Teugbyeolsi, Korea, Republic Of +16 more

Efficacy of Hypomethylating Agents vs. Intensive Chemotherapy in Acute Myeloid Leukemia Using 5hmC as a Blood-Based Minimal Residual Disease Marker

NCT ID: NCT07060001

This clinical trial is studying a new way to monitor and treat adults newly diagnosed with acute myeloid leukemia (AML), a type of blood cancer. Researchers are testing whether a blood test that lo...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States

A Phase 1b/2 Open-label, Dose-ranging Safety and Efficacy Study of Oral Cladribine in Patients With Acute Myeloid Leukemia (AML)

NCT ID: NCT07053020

This clinical trial is studying a new treatment approach for people with Acute Myeloid Leukemia (AML), a type of blood cancer. Researchers want to find the safest and most effective dose of an oral...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

NCT ID: NCT07007312

This clinical trial is studying a new drug called ziftomenib for patients with acute myeloid leukemia (AML) who have specific genetic changes. The goal is to see if adding ziftomenib to standard tr...

Not yet recruiting

Phase: PHASE3 Type: interventional

Thiotepa Combined With Busulfan and Fludarabine Conditioning Regimen for Haploidentical Hematopoietic Stem Cell Transplantation in Elderly Patients With High-Risk Acute Myeloid Leukemia

NCT ID: NCT06869265

This clinical trial is investigating a new treatment approach for older patients (aged 55 to 70) with high-risk acute myeloid leukemia (AML), a type of blood cancer that can be difficult to treat. ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Beijing, Beijing, China

APVO436 Phase 1b/2 Study in Patients With Newly Diagnosed AML

NCT ID: NCT06634394

The APVO436 clinical trial is a research study aimed at finding the best dose of a new treatment called APVO436, which is being tested alongside two other medications, venetoclax and azacitidine, f...

Recruiting

Phase: PHASE1 Type: interventional Locations: Miami, Florida, United States, Dallas, Texas, United States +5 more

A Phase 1 Study of STX-0712 in Patients With Advanced Hematological Malignancies (CMML and AML)

NCT ID: NCT06950034

This clinical trial is studying a new treatment called STX-0712 for patients with advanced forms of blood cancers known as Chronic Myelomonocytic Leukemia (CMML) and Acute Myeloid Leukemia (AML). T...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

Biomarkers in Patients With Anemia-Induced Thrombocytopenic Bleeding

NCT ID: NCT06947044

This clinical trial is looking at how different levels of hemoglobin in the blood affect bleeding in patients with acute leukemia, specifically acute myeloid leukemia (AML) and acute lymphocytic le...

Recruiting

Phase: NA Type: interventional Locations: Hamilton, Ontario, Canada

An Open-label Phase 3b Study of Ivosidenib in Combination With Azacitidine in Adult Patients Newly Diagnosed With IDH1m Acute Myeloid Leukemia (AML) Ineligible for Intensive Induction Chemotherapy.

NCT ID: NCT05907057

This clinical trial is looking at a new combination treatment for adults with a type of blood cancer called acute myeloid leukemia (AML), specifically for those with a certain gene mutation known a...

Recruiting

Phase: PHASE3 Type: interventional Locations: Madrid, , Spain, Groningen, , Netherlands +44 more

Clinical Trial of BP1001 in Combination With With Venetoclax Plus Decitabine in AML

NCT ID: NCT02781883

This clinical trial is studying a new treatment combination for adults with Acute Myeloid Leukemia (AML), a type of blood cancer. Specifically, researchers want to see if adding a drug called BP100...

Recruiting

Phase: PHASE2 Type: interventional Locations: Los Angeles, California, United States, Houston, Texas, United States +7 more

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