Clinical Trials for Breast Cancer

A Study to Assess the Effectiveness of Trastuzumab Deruxtecan in Chinese Breast Cancer Patients (REFRESH)

NCT ID: NCT06210776

The REFRESH clinical trial is studying the effectiveness of a medication called Trastuzumab Deruxtecan (or T-DXd) for patients with specific types of breast cancer. This study focuses on patients w...

Study to Evaluate the Feasibility of Twice Daily Use of Topical Azelaic Acid in Breast Cancer Patients Undergoing Radiation

NCT ID: NCT06966388

This clinical trial is investigating how practical it is for breast cancer patients undergoing radiation treatment to use a topical cream called azelaic acid at least twice a day. Azelaic acid is a...

Connecting Black Families in Houston, Texas to Hereditary Cancer Genetic Counseling, Genetic Testing, and Cascade Testing by Using a Simple Genetic Risk Screening Tool and Telegenetics

NCT ID: NCT05694559

This clinical trial is focused on helping Black families in Houston learn more about their risk for hereditary cancers, such as breast and colorectal cancer. By using a simple screening tool and te...

A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer

NCT ID: NCT06966453

This clinical trial is studying a new medicine called disitamab vedotin to see how safe and effective it is for treating adults with advanced breast cancer that has spread in the body. Specifically...

Genomic Services Research Program

NCT ID: NCT02595957

The Genomic Services Research Program is a clinical trial focused on understanding the role of genes in conditions like colon cancer and breast cancer. Researchers will look at DNA samples to ident...

Moderate-Intensity Exercise and Pain Sensitization in Breast Cancer Survivors: A Case-Based Study

NCT ID: NCT07128030

This clinical trial is studying whether a supervised exercise program combining moderate-intensity aerobic (like walking or cycling) and strength training can help reduce pain sensitivity in women ...

A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

NCT ID: NCT06790693

This clinical trial is looking at a new treatment for patients with advanced breast cancer that is hormone receptor-positive (HR+) and HER2-negative, specifically for those whose tumors have a muta...

Camrelizumab in Combination With Chemotherapy as Neoadjuvant Treatment in Patients With Early or Locally Advanced Triple-negative Breast Cancer

NCT ID: NCT07107217

This clinical trial is studying a new treatment approach for women with early or locally advanced triple-negative breast cancer (TNBC), a type of breast cancer that can be more aggressive and harde...

Tissue Acquisition and Genomics Analysis of Breast Cancer and Other Gynecologic Malignancies

NCT ID: NCT03762733

Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer

NCT ID: NCT03412877

This clinical trial is studying a new treatment for people with certain types of metastatic cancer, meaning the cancer has spread to other parts of the body and has not responded to standard therap...

Gut Microbiome, Adverse Effects, and Markers Through MEtabolic Reprogramming

NCT ID: NCT06536881

This clinical trial is exploring whether fasting for 24 to 48 hours before chemotherapy can help improve the effectiveness of treatment for women with early-stage breast cancer. The goal is to see ...

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

NCT ID: NCT06172478

This clinical trial is studying a new treatment called HER3-DXd for patients with advanced solid tumors, which are cancers that have spread and cannot be treated with surgery or radiation. The tria...

A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.

NCT ID: NCT07062965

This clinical trial is studying a new medicine called PF-07248144 combined with fulvestrant to treat a certain type of advanced breast cancer. This breast cancer is called HR-positive, HER2-negativ...

Identification of Breast Cancer in Breath Samples Using Trained Detection Dogs

NCT ID: NCT07038785

This clinical trial is exploring a new way to detect breast cancer by using trained dogs and artificial intelligence (AI) to analyze a person’s breath. Women who are already scheduled for routine b...

A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer

NCT ID: NCT06103864

This clinical trial is investigating new treatment options for patients with a specific type of breast cancer known as triple-negative breast cancer (TNBC), which is locally advanced and cannot be ...

A Study of MGC026 in Participants With Advanced Solid Tumors

NCT ID: NCT06242470

This clinical trial is investigating a new treatment called MGC026 for adults with advanced solid tumors, which are types of cancer that have spread or cannot be removed through surgery. The study ...

Psychological Well-being in Patients With Breast Cancer

NCT ID: NCT06590727

This clinical trial is focused on understanding the psychological well-being of women diagnosed with breast cancer. It aims to evaluate not just any psychological distress they might feel, but also...

Study to Investigate Efficacy of a Novel Probiotic on the Bacteriome and Mycobiome of Breast Cancer

NCT ID: NCT04362826

This clinical trial is investigating whether a special type of probiotic called BIOHM can help improve the balance of microorganisms in the breast tissue and gut of women with breast cancer. Resear...

Tablet-based Mobile Health Ultrasound for Point-of-care Breast Cancer Diagnosis in Nigeria

NCT ID: NCT04501419

This clinical trial is focused on improving breast cancer diagnosis in Nigeria by training local radiologists to perform ultrasound-guided breast biopsies. The goal is to ensure that women who come...

Study Evaluating DNA Double-strand Breaks (DSBs) REpair Factors (POLQ, Shieldin Complex and 53BP1) Expression as Biomarker of PARP Inhibitor Resistance in Patients With Deleterious Germline Mutation in BRCA 1/2 and HER2-negative, Metastatic or Locally Advanced Breast Cancer.

NCT ID: NCT05378204

This clinical trial is investigating how certain factors in breast cancer cells relate to the effectiveness of a type of treatment called PARP inhibitors. These treatments are commonly used for pat...