Clinical Trials for Obesity

A Long-Term Study of Tirzepatide (LY3298176) in Adults With Type 1 Diabetes and Obesity or Overweight

NCT ID: NCT06962280

This clinical trial is studying a medication called tirzepatide, which is being tested for its effectiveness and safety in adults with type 1 diabetes who are also overweight or obese. The goal is ...

A Study of Tirzepatide (LY3298176) Compared With Placebo in Adults With Type 1 Diabetes and Obesity or Overweight

NCT ID: NCT06914895

This clinical trial is studying a medication called tirzepatide to see how well it works and how safe it is for adults who have type 1 diabetes and are overweight or obese. If you are interested in...

A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and at Least One Weight-Related Comorbidity

NCT ID: NCT06972459

This clinical trial is studying a medication called orforglipron to see how well it helps people with obesity or overweight lose weight, especially those who have at least one other related health ...

A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Type 2 Diabetes

NCT ID: NCT06972472

This clinical trial is studying a medication called orforglipron to see how well it helps people with obesity or overweight who also have type 2 diabetes manage their blood sugar levels. Participan...

Evaluation of Maridebart Cafraglutide in Adult Participants Without Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight

NCT ID: NCT06858839

This clinical trial is studying a medication called maridebart cafraglutide to see if it can help adults who are overweight or obese lose more weight compared to a placebo, which is an inactive tre...

Trial of the Combination of Alpha-Lipoic Acid and Mirabegron in Women and in Men With Obesity

NCT ID: NCT05713799

This clinical trial is exploring whether a combination of two substances—mirabegron, which is a medication, and alpha-lipoic acid, a dietary supplement—can help people with obesity process food bet...

MEHMO Natural History and Biomarkers

NCT ID: NCT06019182

The MEHMO Natural History and Biomarkers study is looking at a group of conditions known as MEHMO syndrome, which includes issues like intellectual disability, seizures, hormone imbalances, and obe...

Indirect Calorimetry Guided Energy Provision in Critically Ill Patients With Obesity

NCT ID: NCT06053216

The DIRECT trial is a study that aims to find out if a special method called indirect calorimetry can help doctors provide the right amount of energy to critically ill patients who are obese. This ...

Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity

NCT ID: NCT06335771

This clinical trial is studying how certain cells in the fat tissue, called macrophages, behave in people with obesity and related health issues like diabetes and fatty liver disease. The researche...

Human Models of Selective Insulin Resistance: Pancreatic Clamp

NCT ID: NCT06558422

This clinical trial, titled "Human Models of Selective Insulin Resistance: Pancreatic Clamp," is studying how lowering insulin levels affects the way the liver produces glucose and fat in people wh...

Growth Hormone Resistance of Beta-cells in Women and People

NCT ID: NCT06571500

This clinical trial is exploring how beta-cells in the pancreas, which are responsible for making insulin and controlling blood sugar, respond to growth hormone in people who have a family history ...

HealthyTogether: RCT of a Dyadic Weight Management Intervention

NCT ID: NCT06619041

The HealthyTogether trial is studying a new weight management program designed specifically for Veterans and their close friends or family members. This 8-week virtual program aims to help particip...

SELECT-LIFE: A Research Study Looking at Long-term Effects of Semaglutide in People Who Took Part in the SELECT Cardiovascular Outcomes Trial

NCT ID: NCT04972721

The SELECT-LIFE study is a research project designed to look at the long-term effects of a medication called semaglutide in people who participated in a previous study known as the SELECT trial. Th...

Exercise Snacks in Obesity

NCT ID: NCT06924346

This clinical trial, called "Exercise Snacks in Obesity," is looking at how short bursts of exercise combined with behavior change support can help improve health in adults with obesity. Over a per...

Immunoinflammatory Response in Post Cardiac Arrest Syndrome (PCAS)

NCT ID: NCT02664831

This clinical trial, titled "Immunoinflammatory Response in Post Cardiac Arrest Syndrome (PCAS)," is investigating how the body’s immune response and inflammation change after a person has a cardia...

A Research Study of the New Medicine NNC0519-0130 in Male Chinese Participants Living With Excess Body Weight

NCT ID: NCT07004322

This clinical trial is testing a new medicine called NNC0519-0130, developed by Novo Nordisk, for men living in China who have type 2 diabetes and are overweight. The goal is to see how well this n...

Evaluation of RAY1225 in Adult Participants Who Have Obesity or Are Overweight

NCT ID: NCT06893016

This clinical trial is looking at a new treatment called RAY1225 for adults who are overweight or have obesity. The main goal is to see if RAY1225 can help people lose more weight compared to a pla...

A Study of LY3537031 in Overweight, Obese, and Healthy Participants

NCT ID: NCT06606106

This clinical trial is studying a new medication called LY3537031 to see how safe it is and how well it works for different groups of people, including those who are overweight, obese, or healthy. ...

Small Extracellular Vesicles and Insulin Action

NCT ID: NCT05933707

This clinical trial is exploring why some individuals with obesity do not develop related health problems, like type 2 diabetes and heart disease, while others do. The researchers are particularly ...

SMART Pilot Trial of Glycemic Screening Outreach

NCT ID: NCT06915194