Clinical Trials for Acute Myeloid Leukemia Refractory

Find clinical trials for acute myeloid leukemia refractory. Discover research opportunities and treatment options in your area.

19 Active Trials Found

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Intensity Modulated Total Marrow Irradiation in Fully Human Leukocyte Antigen (HLA)-Matched and Partially-HLA Mismatched Allogeneic Transplantation Patients With High-Risk Acute Myeloid Leukemia (AML), Chronic Myeloid Leukemia (CML), and Myelodysplastic Syndrome (MDS)

NCT ID: NCT06802315

This clinical trial is testing a new treatment approach for patients with high-risk blood cancers, specifically Acute Myeloid Leukemia (AML), Chronic Myeloid Leukemia (CML), and Myelodysplastic Syn...

Recruiting

Phase: PHASE2 Type: interventional Locations: Chicago, Illinois, United States

A Study of Natural Killer Cells in Combination With Atezolizumab in People With Acute Myelogenous Leukemia

NCT ID: NCT07011004

This clinical trial is studying a new treatment combining special immune cells called natural killer (NK) cells with a medication called atezolizumab for people with acute myeloid leukemia (AML) wh...

Recruiting

Phase: PHASE1 Type: interventional Locations: New York, New York, United States, Middletown, New Jersey, United States +5 more

Master Framework For Relapse or Refractory Acute Myeloid Leukemia

NCT ID: NCT06459024

This clinical trial is focused on understanding the experiences of patients with acute myeloid leukemia (AML) who have either relapsed (the cancer returned after treatment) or are refractory (the c...

Recruiting

Type: observational Locations: Roma, Rm, Italy, Como, Co, Italy +28 more

A Study of CD371-YSNVZIL-18 CAR T Cells in People With Acute Myeloid Leukemia

NCT ID: NCT06017258

This clinical trial is investigating a new treatment called CD371-YSNVZ-IL18 CAR T cells for people with a type of blood cancer known as Acute Myeloid Leukemia (AML), specifically for those whose c...

Recruiting

Phase: PHASE1 Type: interventional Locations: Middletown, New Jersey, United States, Montvale, New Jersey, United States +5 more

Phase 1 Study of Allo-RevCAR01-T-CD123 in Patients With Selected CD123 Positive Hematologic Malignancies

NCT ID: NCT05949125

This clinical trial is investigating a new treatment called Allo-RevCAR01-T-CD123 for patients with certain types of blood cancers, specifically Acute Myeloid Leukemia (AML) that has either come ba...

Recruiting

Phase: PHASE1 Type: interventional Locations: Ulm, , Germany, Hannover, , Germany +10 more

A Study to Investigate APL-4098 Alone and/or in Combination With Azacitidine in R/R AML and High-Risk MDS

NCT ID: NCT06372717

This clinical trial is looking at a new treatment called APL-4098, both on its own and combined with another medication called azacitidine. The goal is to see how safe and effective these treatment...

Recruiting

Phase: PHASE1 Type: interventional Locations: Perth, Western Australia, Australia, Melbourne, Victoria, Australia +5 more

Clinical Study of ARD103 CAR-T Therapy for Patients With R/R AML or MDS

NCT ID: NCT06680752

This clinical trial is studying a new treatment called ARD103 CAR-T therapy for patients with relapsed or refractory acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). The goal is to f...

Recruiting

Phase: PHASE1 Type: interventional Locations: Charlotte, North Carolina, United States, Winston Salem, North Carolina, United States

Study of REM-422 in Patients With AML or Higher Risk MDS

NCT ID: NCT06297941

This clinical trial is studying a new treatment called REM-422 for patients with higher-risk myelodysplastic syndromes (MDS) or acute myeloid leukemia (AML) that has come back after treatment. The ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Jacksonville, Florida, United States +8 more

Off-the-shelf CD123 CAR-NK for R/R AML

NCT ID: NCT06201247

This clinical trial is studying a new treatment called JD123 injection, which uses specially engineered immune cells (CAR-NK cells) to target and fight acute myeloid leukemia (AML) that has either ...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Beijing, Beijing, China

A Clinical Trial of BP1002 in Patients With Refractory/Relapsed Acute Myeloid Leukemia (AML)

NCT ID: NCT05190471

This clinical trial is studying a new treatment called BP1002 for adults with a type of blood cancer known as refractory or relapsed Acute Myeloid Leukemia (AML). This means the cancer has not resp...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States, Los Angeles, California, United States +2 more

KPT-9274 in Patients with Relapsed and Refractory Acute Myeloid Leukemia

NCT ID: NCT04914845

This clinical trial is studying a new oral medication called KPT-9274 to see how safe it is for patients with relapsed or refractory acute myeloid leukemia (AML), which means that their cancer has ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Aurora, Colorado, United States, Aurora, Colorado, United States

Venetoclax to Augment Epigenetic Modification and Chemotherapy

NCT ID: NCT05317403

This clinical trial is studying a new way to treat patients with acute myeloid leukemia (AML) who are either experiencing a relapse or have not responded to previous treatments. The researchers wan...

Recruiting

Phase: PHASE1 Type: interventional Locations: Milwaukee, Wisconsin, United States

PLAT-08: a Study of SC-DARIC33 CAR T Cells in Pediatric and Young Adults with Relapsed or Refractory CD33+ AML

NCT ID: NCT05105152

The PLAT-08 clinical trial is studying a new type of treatment for young people with a specific form of leukemia called acute myeloid leukemia (AML) that has either returned after treatment or did ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Seattle, Washington, United States

Study of Iadademstat and Gilteritinib in Patients With R/R AML With FMS-like Tyrosine Kinase Mutation (FLT3 Mut+)

NCT ID: NCT05546580

This clinical trial is investigating a new treatment combination for patients with relapsed or refractory acute myeloid leukemia (AML) that has a specific genetic mutation known as FLT3. The study ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Durham, North Carolina, United States, Morgantown, West Virginia, United States +14 more

Natural Killer-cell Therapy for Acute Myeloid Leukemia

NCT ID: NCT04347616

This clinical trial is exploring a new treatment for adults with acute myeloid leukemia (AML) that has either come back after treatment (relapsed) or did not respond to previous therapies (refracto...

Recruiting

Phase: PHASE1 Type: interventional Locations: Nijmegen, , Netherlands

An Adaptive Open-label Multicentre Phase 1/2 Trial, to Determine the Recommended Phase 2 Dose of CCTx-001, and to Assess Safety, Tolerability, and Clinical Activity in Patients With Relapsed/Refractory Acute Myeloid Leukaemia

NCT ID: NCT06281847

This clinical trial is studying a new treatment called CCTx-001 for adults with relapsed or refractory acute myeloid leukemia (AML), a type of blood cancer that has returned or hasn’t responded to ...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Stockholm, , Sweden, Ulm, , Germany +4 more

Administration of Anti Tim-3/CD123 CAR-T Cell Therapy in Relapsed and Refractory Acute Myeloid Leukemia (rr/AML)

NCT ID: NCT06125652

This clinical trial is studying a new treatment called anti Tim-3/CD123 CAR-T cell therapy for patients with relapsed or refractory acute myeloid leukemia (AML), which means their leukemia has come...

Recruiting

Phase: PHASE1 Type: interventional Locations: Xuzhou, Jiangsu, China

AB8939 in Patients With Relapsed/Refractory Acute Myeloid Leukemia

NCT ID: NCT05211570

This clinical trial is testing a new treatment called AB8939 for patients with acute myeloid leukemia (AML) who have either not responded to previous treatments or whose cancer has come back. The m...

Recruiting

Phase: PHASE1 Type: interventional Locations: Madrid, , Spain, Houston, Texas, United States +10 more

Treatment With ABT-199 (Venetoclax) and Purine Analogues in Relapsed/Refractory Acute Myeloid Leukemia

NCT ID: NCT05506332

This clinical trial is studying a new treatment approach for adults with acute myeloid leukemia (AML) who have not responded to previous therapies or whose cancer has returned after treatment. The ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Edegem, Antwerp, Belgium, Roeselare, West Vlaanderen, Belgium

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