Clinical Trials for Acute Myeloid Leukemia

Find clinical trials for acute myeloid leukemia. Discover research opportunities and treatment options in your area.

354 Active Trials Found

Showing 354 trials on this page

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Dose Escalation and Expansion of Ziftomenib in Combination With Quizartinib in Acute Myeloid Leukemia

NCT ID: NCT06769490

This clinical trial is studying a new treatment for adults with a type of blood cancer called acute myeloid leukemia (AML). The researchers want to see if a combination of two oral medications, Zif...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

A Safety Study of SEA-CD70 in Patients With Myeloid Malignancies

NCT ID: NCT04227847

This clinical trial is studying a new drug called SEA-CD70, which is being tested to see if it is safe and effective for patients with myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, New York, New York, United States +64 more

A Study to Assess Change in Disease State in Adult Participants With Acute Myeloid Leukemia (AML) Receiving Oral Venetoclax Tablets in Combination With Subcutaneously (SC) or Intravenously (IV) Injected Azacitidine in Colombia

NCT ID: NCT05587049

This clinical trial is investigating how well a combination of two medications, venetoclax and azacitidine, works to treat a type of blood cancer called acute myeloid leukemia (AML) in adults in Co...

Recruiting

Type: observational Locations: Medellin, Antioquia, Colombia, Barranquilla, Atlantico, Colombia +14 more

A Study to Assess Change in Disease State in Adult Participants With Acute Myeloid Leukemia (AML) Ineligible for Intensive Chemotherapy Receiving Oral Venetoclax Tablets in Canada

NCT ID: NCT05424562

This clinical trial is studying a medication called venetoclax, which is used to treat Acute Myeloid Leukemia (AML), a type of blood cancer. The focus of the trial is to see how effective venetocla...

Recruiting

Type: observational Locations: Calgary, Alberta, Canada, Vancouver, British Columbia, Canada +23 more

Efficacy of Integrated Induction-Consolidation Chemotherapy and Transplantation for Adult Acute Myeloid Leukemia: Multicenter Study

NCT ID: NCT07108530

This clinical trial is studying a new treatment plan for adults diagnosed with a type of blood cancer called acute myeloid leukemia (AML), except for one specific subtype (called AML-M3). The goal ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Taiyuan, Shanxi, China

Testing the Anti-cancer Drug, Cirtuvivint, and Its Combination With ASTX727 to Improve Outcomes in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndromes

NCT ID: NCT06484062

This clinical trial is studying a new anti-cancer drug called cirtuvivint, both by itself and in combination with another treatment known as ASTX727. The goal is to see if these treatments can help...

Recruiting

Phase: PHASE1 Type: interventional Locations: Chicago, Illinois, United States, Boston, Massachusetts, United States

Iadademstat in Combination With Azacitidine and Venetoclax in Treating Newly Diagnosed Acute Myeloid Leukemia

NCT ID: NCT06357182

This clinical trial is studying a new treatment approach for patients with newly diagnosed acute myeloid leukemia (AML), a type of blood cancer. Researchers want to find out how safe it is to use a...

Recruiting

Phase: PHASE1 Type: interventional Locations: Portland, Oregon, United States

Pilot Study of Memory-like Natural Killer (ML NK) Cells After TCRαβ T Cell Depleted Haploidentical Transplant in AML

NCT ID: NCT06158828

This clinical trial is exploring a new approach to improve stem cell transplants for children and young adults with high-risk acute myeloid leukemia (AML). The study involves patients receiving a s...

Recruiting

Phase: PHASE1 Type: interventional Locations: Saint Louis, Missouri, United States

Phase III Study of Induction and Consolidation Chemotherapy With Venetoclax in Patients With Newly Diagnosed AML or MDS-EB-2

NCT ID: NCT04628026

This clinical trial is studying a new treatment for adults with newly diagnosed acute myeloid leukemia (AML) or myelodysplastic syndromes with excess blasts (MDS-EB-2). The researchers want to see ...

Recruiting

Phase: PHASE3 Type: interventional Locations: Hamburg, Germany, Enschede, Netherlands +83 more

The Prognostic Significance of Platelet to White Blood Cell Ratio (PWR) in Patients With Acute Myeloid Leukemia

NCT ID: NCT07115537

This clinical trial is studying whether a simple blood test measuring the ratio between platelets and white blood cells (called the Platelet to White Blood Cell Ratio, or PWR) can help predict outc...

Not yet recruiting

Type: observational

Decitabine and Venetoclax Treatment as Maintenance Therapy in Patients Post Allograft Stem Cell Transplant

NCT ID: NCT06129734

This clinical trial is exploring a new treatment approach for patients who have had a bone marrow transplant due to conditions like acute myeloid leukemia or myelodysplastic syndromes. The study ai...

Recruiting

Phase: PHASE1 Type: interventional Locations: Cleveland, Ohio, United States

A Study of Azacitidine and Venetoclax Versus a Stem Cell Transplant in People 65 Years and Older With Acute Myeloid Leukemia

NCT ID: NCT06903702

This clinical trial is looking at two different treatments for older adults (65 years and older) with acute myeloid leukemia (AML). Researchers want to see whether a stem cell transplant or a combi...

Recruiting

Phase: PHASE2 Type: interventional Locations: New York, New York, United States, Middletown, New Jersey, United States +5 more

First in Human Study of Ziftomenib in Relapsed or Refractory Acute Myeloid Leukemia

NCT ID: NCT04067336

This clinical trial is testing a new medication called ziftomenib in patients with acute myeloid leukemia (AML) who have not responded to other treatments or whose cancer has returned. The trial is...

Recruiting

Phase: PHASE1 Type: interventional Locations: Chicago, Illinois, United States, Rochester, Minnesota, United States +64 more

A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)

NCT ID: NCT04811560

This clinical trial is studying a new treatment called bleximenib for patients with acute leukemia, which includes types like acute myeloid leukemia and acute lymphoblastic leukemia. The main goal ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Orange, California, United States, Boston, Massachusetts, United States +112 more

Chidamide, Venetoclax, and Azacitidine for Newly Diagnosed Acute Myeloid Leukemia

NCT ID: NCT06386302

This clinical trial is looking at a new treatment approach for patients with newly diagnosed acute myeloid leukemia (AML) who are not able to undergo intensive chemotherapy. The study is testing a ...

Recruiting

Phase: NA Type: interventional Locations: Tianjin, Tianjin, China

A Prospective Trial of Dalbavancin-Based Prophylaxis in Children and Adolescents With High-Risk Leukemia

NCT ID: NCT06810583

This clinical trial is looking at the use of a medication called dalbavancin to help prevent serious bacterial infections in children and young adults who are being treated for high-risk leukemia, ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Memphis, Tennessee, United States

Chemotherapy (Decitabine in Combination With FLAG-Ida) and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Adults With Myeloid Malignancies at High Risk of Relapse

NCT ID: NCT06928662

This clinical trial is investigating a new treatment approach for adults with certain types of blood cancers, specifically those at high risk of their cancer returning. The treatment combines a med...

Recruiting

Phase: PHASE1 Type: interventional Locations: Seattle, Washington, United States

Combination Chemotherapy (FLAG-Ida) Followed Immediately by Reduced-Intensity Total Body Radiation Therapy and Donor Hematopoietic Cell Transplant for the Treatment of Adults Age 60 and Older With Newly Diagnosed Adverse-Risk Acute Myeloid Leukemia or Other High-Grade Myeloid Cancer

NCT ID: NCT07046078

This clinical trial is studying a new treatment approach for adults aged 60 and older who have been recently diagnosed with a high-risk form of acute myeloid leukemia (AML) or other similar serious...

Recruiting

Phase: PHASE2 Type: interventional Locations: Seattle, Washington, United States

CD180 CART for Relapsed or Refractory CD180 Positive Hematologic Malignancies

NCT ID: NCT07106749

This clinical trial is testing a new treatment called CD180 CAR-T therapy for adults with certain types of blood cancers—specifically, acute myeloid leukemia (AML) and B-cell acute lymphoblastic le...

Recruiting

Phase: PHASE1 Type: interventional Locations: Tianjin, Tianjin, China

Safety and Proof-of-Concept Study of RPT1G in Adults With Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndromes

NCT ID: NCT07107126

This clinical trial is studying a new medicine called RPT1G to see if it is safe and well-tolerated in adults who have a type of blood cancer called acute myeloid leukemia (AML) or a related bone m...

Not yet recruiting

Phase: PHASE1 Type: interventional

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