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Clinical Trials for Advanced Hepatocellular Carcinoma

Find clinical trials for advanced hepatocellular carcinoma. Discover research opportunities and treatment options in your area.

45 Active Trials Found

Showing 45 trials on this page

Page 1 of 3

Autologous CAR T Cells Targeting GPC3 (RPCAR01) for the Treatment of Advanced or Metastatic GPC3 Expressing Hepatocellular Carcinoma

NCT ID: NCT06968195

This clinical trial is investigating a new treatment called RPCAR01 for patients with advanced liver cancer known as hepatocellular carcinoma (HCC). Specifically, the trial focuses on patients whos...

Not yet recruiting
Phase: PHASE1 Type: interventional Locations: Buffalo, New York, United States

A Study to Evaluate ALN-BCAT in Patients With Hepatocellular Carcinoma

NCT ID: NCT06600321

This clinical trial is studying a new treatment called ALN-BCAT for people with advanced liver cancer, specifically a type known as hepatocellular carcinoma (HCC). The trial has two main parts: the...

Recruiting
Phase: PHASE1 Type: interventional Locations: Chicago, Illinois, United States, Dallas, Texas, United States +10 more

Testing the Addition of an Anti-cancer Drug, Sapanisertib, to the Usual Chemotherapy Treatment (Cabozantinib) in Metastatic Liver Cell Cancer With a Change in Genes for the Protein β-Catenin, The SAPHIRE Trial

NCT ID: NCT06811116

This clinical trial is investigating the combination of two anti-cancer drugs, sapanisertib and cabozantinib, to see if they are more effective together for treating advanced liver cancer (hepatoce...

Recruiting
Phase: PHASE1 Type: interventional Locations: Pittsburgh, Pennsylvania, United States

A Study of BL-B01D1 Combined With Lenvatinib in Patients With Advanced Hepatocellular Carcinoma

NCT ID: NCT06986785

This clinical trial is studying a new treatment approach for patients with advanced liver cancer, specifically hepatocellular carcinoma (HCC). Researchers want to find out if combining two medicati...

Not yet recruiting
Phase: PHASE2 Type: interventional Locations: Shanghai, Shanghai, China

Study of SHR-8068 Combined With Adebrelimab and Bevacizumab Versus Sintilimab Combined With Bevacizumab for the Treatment of Advanced Hepatocellular Carcinoma

NCT ID: NCT06618664

This clinical trial is looking at two different treatment combinations for patients with advanced liver cancer, also known as hepatocellular carcinoma (HCC). Specifically, it compares a new treatme...

Recruiting
Phase: PHASE3 Type: interventional Locations: Hefei, Anhui, China

A Study of Tegavivint (BC2059) in Patients With Advanced Hepatocellular Carcinoma

NCT ID: NCT05797805

This clinical trial is investigating a new treatment called Tegavivint (BC2059) for patients with advanced liver cancer, specifically a type known as hepatocellular carcinoma (HCC) that has not res...

Recruiting
Phase: PHASE1 Type: interventional Locations: Minneapolis, Minnesota, United States, Chicago, Illinois, United States +7 more

Study of AU409 Capsule in Advanced Hepatocellular Carcinoma Patients Who Failed Standard Treatment

NCT ID: NCT06374485

This clinical trial is investigating a new treatment called AU409 for patients with advanced liver cancer, specifically those who have not had success with standard therapies. The study is in its e...

Recruiting
Phase: PHASE1 Type: interventional Locations: Hong Kong, , China

A Clinical Trial Evaluating the Safety and Efficacy of Intravenous CD-801 in Treating Advanced HCC Patients

NCT ID: NCT06418659

This clinical trial is looking at a new treatment called CD-801 for patients with advanced liver cancer, specifically hepatocellular carcinoma (HCC). The main goals of the study are to check how sa...

Recruiting
Phase: EARLY_PHASE1 Type: interventional Locations: Shanghai, Shanghai, China

A Phase 1 Study of BGB-B2033, Alone or in Combination With Tislelizumab, in Participants With Advanced or Metastatic Solid Tumors

NCT ID: NCT06427941

This clinical trial is studying a new treatment called BGB-B2033, which is being tested alone and in combination with another medication called tislelizumab. The goal is to see how safe BGB-B2033 i...

Recruiting
Phase: PHASE1 Type: interventional Locations: Seoul, , Korea, Republic Of, Auckland, , New Zealand +20 more

Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Advanced Solid Tumors Involving the Abdomen or Thorax

NCT ID: NCT05092373

This clinical trial is studying a new treatment approach for patients with advanced solid tumors affecting the abdomen or chest, such as advanced breast, ovarian, or liver cancer. The researchers a...

Recruiting
Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

Cryoablation Combined with Tislelizumab Plus Lenvatinib As Second-line or Later Therapy in Advanced Hepatocellular Carcinoma

NCT ID: NCT05057845

This clinical trial is investigating a new treatment approach for patients with advanced liver cancer, specifically a type called hepatocellular carcinoma. The study is looking at how well a combin...

Recruiting
Phase: PHASE2 Type: interventional Locations: Shanghai, Shanghai, China

Ligufalimab and Cadonilimab in Advanced Liver Cancers

NCT ID: NCT06789848

This clinical trial is exploring whether two drugs, Ligufalimab and Cadonilimab, can effectively treat advanced liver cancers, specifically hepatocellular carcinoma and biliary tract cancer, in pat...

Recruiting
Phase: PHASE2 Type: interventional Locations: Dallas, Texas, United States

Study of ADI-PEG 20 Versus Placebo in Subjects with High Arginine Level and Unresectable Hepatocellular Carcinoma

NCT ID: NCT05317819

This clinical trial is studying a treatment called ADI-PEG 20 to see how well it works for patients with advanced liver cancer, known as hepatocellular carcinoma (HCC), who have high levels of a su...

Recruiting
Phase: PHASE3 Type: interventional Locations: Changhua, , Taiwan, Hanoi, , Vietnam +10 more

Clinical Trial of Autologous CD19 CAR-T Cells (CNCT19) Therapy for Advanced Hepatocellular Carcinoma

NCT ID: NCT06676982

This clinical trial is exploring a new treatment called CNCT19 CAR-T cell therapy for patients with advanced hepatocellular carcinoma, which is a type of liver cancer. The main goal of the study is...

Not yet recruiting
Phase: PHASE1 Type: interventional Locations: Hangzhou, Zhejiang, China

68Ga PSMA PET Imaging for the Treatment of Advanced Liver Cancer

NCT ID: NCT05176223

This clinical trial is studying a new imaging technique called 68Ga-PSMA PET to see if it can help doctors better diagnose and manage advanced liver cancer. In this trial, the researchers are focus...

Recruiting
Phase: PHASE2 Type: interventional Locations: Rochester, Minnesota, United States

Ablation of Pulmonary Oligometastasis Combined With System for Advanced Hepatocellular Carcinoma

NCT ID: NCT06644430

This clinical trial is exploring a treatment option for patients with advanced liver cancer (hepatocellular carcinoma) that has spread to the lungs (known as pulmonary oligometastasis). The study a...

Recruiting
Type: observational Locations: Beijing, Beijing, China

dTACE-HAIC Combined With Bevacizumab and Atezolizumab for Huge Hepatocellular Carcinoma

NCT ID: NCT06609863

This clinical trial is studying a new treatment approach for patients with advanced liver cancer, specifically a type called hepatocellular carcinoma (HCC). The treatment combines several methods: ...

Recruiting
Phase: NA Type: interventional Locations: Beijing, None Selected, China

Clinical Study of TQB2223 Injection Combined With AK105 Injection in the Treatment of Advanced Hepatocellular Carcinoma.

NCT ID: NCT06320080

This clinical trial is studying the combination of two injections, TQB2223 and AK105, to see if they can help treat advanced liver cancer, specifically a type called hepatocellular carcinoma. The m...

Recruiting
Phase: PHASE1 Type: interventional Locations: Harbin, Heilongjiang, China, Wuhan, Hubei, China +1 more

Rituximab Combined With Prior Therapy in Advanced Hepatocellular Carcinoma: Efficacy & Safety Study

NCT ID: NCT06301399

This clinical trial is investigating the effectiveness and safety of a medication called rituximab for patients with advanced liver cancer, known as hepatocellular carcinoma (HCC), who have not res...

Recruiting
Phase: PHASE2 Type: interventional Locations: Tianjin, Tianjin, China

Clinical Trial of Autologous GPC3 CAR-T Cells (CBG166) Therapy for Advanced Hepatocellular Carcinoma

NCT ID: NCT06461624

This clinical trial is studying a new treatment for patients with advanced liver cancer, specifically targeting a protein called GPC3. The treatment involves using a special type of immune cells, k...

Recruiting
Phase: PHASE1 Type: interventional Locations: Hangzhou, Zhejiang, China, Hangzhou, Zhejiang, China +1 more

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