Clinical Trials for Advanced Malignant Solid Neoplasm

Impact of Project ECHO on Improving the Quality of Palliative Care in Patients With Advanced Cancer and Their Caregivers in Underserved Areas of Kenya, Nigeria, Ghana, South Africa, India, and Ethiopia

NCT ID: NCT04984551

This clinical trial is looking at how to improve the care and support provided to patients with advanced cancer and their caregivers in underserved areas of Kenya, Nigeria, Ghana, South Africa, Ind...

Testing A New Anti-cancer Drug Combination, Entinostat and ZEN003694, for Advanced and Refractory Solid Tumors and Lymphomas

NCT ID: NCT05053971

This clinical trial is exploring a new combination of two anti-cancer drugs, entinostat and ZEN003694, to see how safe they are and how well they work for patients with advanced solid tumors or lym...

Talazoparib and Palbociclib, Axitinib, or Crizotinib for the Treatment of Advanced or Metastatic Solid Tumors, TalaCom Trial

NCT ID: NCT04693468

The TalaCom Trial is a research study looking at how well a new treatment called talazoparib works when combined with other drugs (palbociclib, axitinib, or crizotinib) for patients with advanced o...

At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer

NCT ID: NCT05969860

This clinical trial is exploring whether cancer treatment can be more effective and convenient when given at home instead of in a clinic. The study focuses on patients with advanced cancer that has...

Adoption of Audio Recording in the Outpatient Supportive Care Center

NCT ID: NCT04871477

This clinical trial is looking at how patients with advanced cancer feel about having their clinic visits recorded. The goal is to see if audio recordings can help patients remember important infor...

Siltuximab for the Prevention of Severe Immune-Related Adverse Events During Immune Checkpoint Inhibitor Rechallenge in Patients with Advanced Cancer, CIRES Trial

NCT ID: NCT06470971

The CIRES Trial is a clinical study looking at how effective a medication called siltuximab is in preventing serious side effects when patients with advanced cancer undergo a second round of treatm...

Group Meaning-Centered Psychotherapy for the Improvement of Wellbeing in Caregivers of Patients with Advanced Cancer

NCT ID: NCT06630351

Trifluridine/Tipiracil and Talazoparib for the Treatment of Patients With Locally Advanced or Metastatic Colorectal or Gastroesophageal Cancer

NCT ID: NCT04511039

This clinical trial is studying the combination of two cancer treatments, trifluridine/tipiracil and talazoparib, to see how well they work together for patients with advanced colorectal or gastroe...

AU409 for the Treatment of Advanced Primary Liver Cancers or Solid Tumor With Liver Metastatic Disease

NCT ID: NCT05791448

This clinical trial is testing a new treatment called AU409 for patients with advanced liver cancers or solid tumors that have spread to the liver. The main goal is to find out if AU409 is safe, ho...

A Cancer Vaccine (Labvax 3(22)-23) and GM-CSF Alone or in Combination With Pembrolizumab for the Treatment of Advanced Stage Adenocarcinoma

NCT ID: NCT05101356

This clinical trial is investigating a new cancer vaccine called Labvax 3(22)-23, combined with a therapy called GM-CSF, and possibly with another drug called pembrolizumab, to treat advanced stage...

FID-007 in Treating Participants With Advanced Solid Tumors

NCT ID: NCT03537690

This clinical trial, called FID-007, is investigating a new treatment for patients with advanced solid tumors that have not responded to standard therapies. The treatment being studied is a special...

CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors

NCT ID: NCT05733000

This clinical trial is investigating a new treatment approach for patients with certain advanced cancers that have not responded to standard chemotherapy. The study is testing a combination of thre...