Clinical Trials for Advanced Melanoma

Find clinical trials for advanced melanoma. Discover research opportunities and treatment options in your area.

32 Active Trials Found

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VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs (IGNYTE-3)

NCT ID: NCT06264180

The IGNYTE-3 clinical trial is studying a new treatment option for patients with advanced melanoma (a type of skin cancer) that has not responded to previous therapies. Specifically, the trial is c...

Recruiting

Phase: PHASE3 Type: interventional Locations: Minneapolis, Minnesota, United States, Iowa City, Iowa, United States +40 more

AB821 in Adult Participants With Locally Advanced or Metastatic Solid Tumors

NCT ID: NCT07027488

This clinical trial is testing a new medicine called AB821 in adults with advanced melanoma (a serious type of skin cancer) or other solid tumors that respond to immune-based treatments. The main g...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: New Haven, Connecticut, United States

Neoadjuvant and Adjuvant Anti-PD1 or Combinations for Locoregionally Advanced Melanoma

NCT ID: NCT06295159

This clinical trial is studying a new type of treatment for patients with advanced melanoma, which is a serious skin cancer. The goal is to see if using immunotherapy—medications that help the body...

Recruiting

Phase: PHASE2 Type: interventional Locations: Tampa, Florida, United States

IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma (PRISM-MEL-301)

NCT ID: NCT06112314

This clinical trial, called PRISM-MEL-301, is exploring a new treatment for patients with advanced melanoma, specifically looking at a combination of two medications: IMC-F106C and nivolumab. The s...

Recruiting

Phase: PHASE3 Type: interventional Locations: New York, New York, United States, Edmonton, , Canada +206 more

Efficacy and Safety of Iparomlimab and Tuvonralimab Injection in Combination With Bevacizumab After Progression on Anti-PD-(L)1 Therapy in Advanced Melanoma: A Prospective, Single-Arm, Exploratory Clinical Study

NCT ID: NCT07004335

This clinical trial is looking at a new treatment approach for patients with advanced melanoma (a serious type of skin cancer) who have not responded well to previous immunotherapy treatments. The ...

Not yet recruiting

Phase: PHASE4 Type: interventional Locations: Shijiazhuang, , China

A Trial of Pembrolizumab and Metformin Versus Pembrolizumab Alone in Advanced Melanoma

NCT ID: NCT03311308

This clinical trial is testing a new treatment approach for patients with advanced melanoma, a serious skin cancer. Researchers want to see if combining two medications—Pembrolizumab (also known as...

Recruiting

Phase: PHASE1 Type: interventional Locations: Pittsburgh, Pennsylvania, United States

Memory-Like Natural Killer Cells With Nivolumab and Relatlimab in Advanced or Metastatic Melanoma After Progression on Checkpoint Inhibitors

NCT ID: NCT05629546

This clinical trial is exploring a new treatment approach for patients with advanced or metastatic melanoma, a serious skin cancer that has spread beyond its original site. Researchers are testing ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Saint Louis, Missouri, United States

Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

NCT ID: NCT05549297

The TEBE-AM clinical trial is studying a new treatment for patients with advanced melanoma, which is a serious type of skin cancer. This trial is comparing a medication called tebentafusp, both on ...

Recruiting

Phase: PHASE3 Type: interventional Locations: Boston, Massachusetts, United States, New York, New York, United States +78 more

HS-IT101 Injection in the Treatment of Advanced Melanoma

NCT ID: NCT06941818

This clinical trial is investigating a new treatment called HS-IT101 for patients with advanced melanoma, which is a serious type of skin cancer. The study will use a method called adoptive cell th...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Beijing, , China

Safety and Efficacy of EIK1001-006 in Combo With Pembro Versus Placebo and Pembro as First-Line Therapy in Patients With Advanced Melanoma.

NCT ID: NCT06697301

This clinical trial is studying a new treatment combination for patients with advanced melanoma, a serious skin cancer, who are eligible for a standard therapy called Pembrolizumab. The trial aims ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Colorado Springs, Colorado, United States, Auckland, , New Zealand +10 more

IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors

NCT ID: NCT05039801

This clinical trial is studying a new treatment called IACS-6274 for patients with advanced solid tumors, which are types of cancer that have spread beyond their original site. The trial is looking...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

The Immune Effects of Fermented Wheat Germ Nutritional Supplementation in Patients With Advanced Solid Tumor Cancers Being Treated With Standard of Care Checkpoint Inhibitors

NCT ID: NCT05967533

This clinical trial is studying the effects of a nutritional supplement called fermented wheat germ on the immune system of patients with advanced solid tumor cancers, such as lung cancer, melanoma...

Recruiting

Phase: PHASE1 Type: interventional Locations: Sacramento, California, United States

NY-ESO-1-redirected T Cells in Patients With Advanced Melanoma and Sarcoma

NCT ID: NCT06889766

This clinical trial is studying a new treatment for patients with advanced melanoma or sarcoma, which are types of skin and soft tissue cancers. The treatment involves using specially trained immun...

Recruiting

Phase: PHASE1 Type: interventional Locations: Lausanne, Vaud, Switzerland, Lausanne, Vd, Switzerland

High-Intensity Exercise and High-Fiber Diet for Immunotherapy Outcomes in Melanoma Patients: The DUO Trial

NCT ID: NCT06298734

The DUO Trial is a research study designed to see if high-intensity exercise and a high-fiber diet can help improve health outcomes for patients with advanced melanoma who are receiving a type of t...

Recruiting

Phase: NA Type: interventional Locations: Boston, Massachusetts, United States

A Clinical Study of T3011 in Subjects With Advanced Melanoma

NCT ID: NCT06214156

This clinical trial is studying a new treatment called T3011 for patients with advanced melanoma, which is a serious type of skin cancer. The main goals of the study are to see how well the treatme...

Recruiting

Phase: PHASE1 Type: interventional Locations: Beijing, , China, Changchun, Jilin, China +8 more

ACT-TIL and ANV419 for Advanced Melanoma.

NCT ID: NCT05869539

The ACT-TIL and ANV419 trial is studying a new treatment approach for patients with advanced melanoma, which is a serious type of skin cancer. The goal of this trial is to evaluate the safety and t...

Recruiting

Phase: PHASE1 Type: interventional Locations: Basel, Bs, Switzerland

Study on TIL for the Treatment of Advanced Melanoma

NCT ID: NCT05098184

This clinical trial is focused on a new treatment for advanced melanoma, a type of skin cancer. The researchers are studying a therapy called tumor-infiltrating lymphocyte (TIL) therapy, which uses...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Shanghai, Shanghai, China

A Study to Assess LBL-007 in Combination With Toripalimab and Axitinib Tablets Subjects With Advanced Melanoma

NCT ID: NCT04640545

This clinical trial is investigating a new treatment called LBL-007, which is being tested alongside two existing medications, Toripalimab and Axitinib, for patients with advanced melanoma, a type ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Chengdu, Sichuan, China, Changchun, Jilin, China +10 more

A Study of Fianlimab, Cemiplimab, and Ipilimumab in People With Melanoma

NCT ID: NCT06594991

This clinical trial is investigating a new treatment for advanced melanoma, a serious form of skin cancer that has spread and cannot be surgically removed. Researchers want to see if using three me...

Recruiting

Phase: PHASE2 Type: interventional Locations: Los Angeles, California, United States, New York, New York, United States +9 more

Peripheral T Cell Determinants of Response and Resistance to Pembrolizumab in Melanoma

NCT ID: NCT05105100

This clinical trial is studying how certain immune cells in the body, called T cells, can help predict how well patients with advanced melanoma will respond to a treatment called pembrolizumab. The...

Recruiting

Type: observational Locations: San Francisco, California, United States

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