Clinical Trials for Advanced or Metastatic Solid Tumors

Find clinical trials for advanced or metastatic solid tumors. Discover research opportunities and treatment options in your area.

19 Active Trials Found

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DCSZ11 as a Monotherapy and in Combination in Patients With Advanced or Metastatic Solid Tumors

NCT ID: NCT05785754

This clinical trial is studying a new treatment called DCSZ11, which is an anti-CD93 monoclonal antibody, in patients who have advanced or metastatic solid tumors. The goal is to see how well DCSZ1...

Recruiting

Phase: PHASE1 Type: interventional Locations: Rochester, Minnesota, United States, Columbus, Ohio, United States +34 more

A Phase 1 Study of LNCB74 in Advanced Solid Tumors

NCT ID: NCT06774963

This clinical trial is studying a new treatment called LNCB74 for patients with advanced solid tumors, which are cancers that have spread and cannot be surgically removed. The trial aims to find ou...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Boston, Massachusetts, United States +8 more

Safety and Tolerability of IPH4502 in Patients With Advanced Solid Tumors

NCT ID: NCT06781983

This clinical trial is exploring a new treatment called IPH4502 for patients with advanced solid tumors, which are cancers that have progressed and cannot be removed by surgery. The main goal of th...

Recruiting

Phase: PHASE1 Type: interventional Locations: Hackensack, New Jersey, United States, Fairfax, Virginia, United States +3 more

Dose Escalation and Expansion Study of HM97662 in Advanced or Metastatic Solid Tumors

NCT ID: NCT05598151

This clinical trial is testing a new drug called HM97662, which is designed to treat advanced or metastatic solid tumors—these are types of cancer that have spread beyond their original site. The s...

Recruiting

Phase: PHASE1 Type: interventional Locations: Seoul, , Korea, Republic Of, Seoul, , Korea, Republic Of +9 more

A Phase 1b/2 Multisite Dose-finding and Expansion Study of WTX-330 in Adult Patients With Selected Advanced or Metastatic Solid Tumors or Lymphoma

NCT ID: NCT06939283

This clinical trial is exploring a new treatment called WTX-330 for adults with advanced or metastatic cancers, including certain types of solid tumors and non-Hodgkin lymphoma. The main goals are ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Scottsdale, Arizona, United States

A Study of PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors

NCT ID: NCT05787587

This clinical trial is studying a new treatment called IDE161 for patients with advanced solid tumors, which are cancers that have spread beyond their original location. The goal is to find out how...

Recruiting

Phase: PHASE1 Type: interventional Locations: Philadelphia, Pennsylvania, United States, New York, New York, United States +28 more

To Evaluate the Safety, Tolerability, Pharmacokinetics and Antitumor Activity of DAY301 in Participants With Locally Advanced or Metastatic Solid Tumors

NCT ID: NCT06752681

This clinical trial is studying a new treatment called DAY301 for patients with advanced or metastatic solid tumors, which are cancers that have spread beyond their original location. The trial aim...

Recruiting

Phase: PHASE1 Type: interventional Locations: San Antonio, Texas, United States, Indianapolis, Indiana, United States +2 more

A Clinical Study of KK2260 in Patients With Advanced or Metastatic Solid Tumors

NCT ID: NCT06248411

This clinical trial is studying a new treatment called KK2260 for patients with advanced or metastatic solid tumors, which are cancers that have spread from where they started. The trial has two pa...

Recruiting

Phase: PHASE1 Type: interventional Locations: Nagoya, Aichi, Japan, Chuo Ku, Tokyo, Japan +8 more

Dose Escalation and Expansion Study of HM16390 in Advanced or Metastatic Solid Tumors

NCT ID: NCT06724016

This clinical trial is studying a new treatment called HM16390 for patients with advanced or metastatic solid tumors, which are cancers that have spread from their original site to other parts of t...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Seoul, , Korea, Republic Of +1 more

Phase I of XKH002 Injection in Patients

NCT ID: NCT06196762

This clinical trial is testing a new treatment called XKH002 Injection for patients with advanced or metastatic solid tumors, which are types of cancer that have spread from their original site. It...

Recruiting

Phase: PHASE1 Type: interventional Locations: Beijing, , China

Dose Escalation and Expansion Study of BH3120 Alone or With Pembrolizuamb in Advanced or Metastatic Solid Tumors

NCT ID: NCT06234397

This clinical trial is looking at a new treatment called BH3120, both by itself and in combination with another medication called pembrolizumab, for patients with advanced or metastatic solid tumor...

Recruiting

Phase: PHASE1 Type: interventional Locations: Hackensack, New Jersey, United States, Seoul, , Korea, Republic Of +9 more

A Study of CHS-1000 in Participants With Advanced or Metastatic Solid Tumors

NCT ID: NCT06389526

This clinical trial is looking at a new treatment called CHS-1000 for patients with advanced or metastatic solid tumors, which are cancers that have spread and cannot be completely removed through ...

Not yet recruiting

Phase: PHASE1 Type: interventional

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

NCT ID: NCT06395519

This clinical trial is studying a new medication called ETX-19477, which targets a specific enzyme involved in cancer growth. Researchers want to find out how safe the drug is, how the body process...

Recruiting

Phase: PHASE1 Type: interventional Locations: New York, New York, United States, Houston, Texas, United States +3 more

Pan-T Booster Co-expressing MSLN CAR T Cell Therapy in Advanced/Metastatic Solid Tumors

NCT ID: NCT05693844

This clinical trial is studying a new treatment called pan-T booster co-expressing MSLN CAR T cell therapy for patients with advanced or metastatic solid tumors. This innovative therapy aims to imp...

Recruiting

Phase: PHASE1 Type: interventional Locations: Beijing, Beijing, China

A First-in-human Study of PRTH-101 Monotherapy +/- Pembrolizumab in Subjects With Advanced Malignancies

NCT ID: NCT05753722

This clinical trial is looking at a new treatment called PRTH-101, both on its own and in combination with another drug called pembrolizumab, for adults with advanced or metastatic solid tumors. Th...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States, New Haven, Connecticut, United States +7 more

A Phase 1 Study to Evaluate TGI-6 in Subjects With Locally Advanced/Metastatic Solid Tumors

NCT ID: NCT06374173

This clinical trial is testing a new treatment called TGI-6 for patients with advanced or metastatic solid tumors, which are cancers that have spread beyond their original site. The study is curren...

Recruiting

Phase: PHASE1 Type: interventional Locations: Beijing, , China

Study to Assess the Safety, Tolerability, and Blood Concentration of PMC-309

NCT ID: NCT05957081

This clinical trial is studying a new treatment called PMC-309 for patients with advanced or metastatic solid tumors, which are cancers that cannot be removed by surgery and have spread to other pa...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Melbourne, Victoria, Australia, Malvern, Victoria, Australia +2 more

Study of MHB088C in Participants With Advanced or Metastatic Solid Tumors

NCT ID: NCT05652855

This clinical trial is studying a new treatment called MHB088C for patients with advanced or metastatic solid tumors, which are types of cancer that have spread beyond their original site. The main...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Melbourne, Victoria, Australia, Gold Coast, Queensland, Australia +1 more

To Evaluate the Safety and Tolerability of SYHX2001 in Patients With Advanced or Metastatic Solid Tumors

NCT ID: NCT05407909

This clinical trial is exploring a new drug called SYHX2001 to see if it is safe and tolerable for patients with advanced or metastatic solid tumors, which are types of cancer that have spread beyo...

Recruiting

Phase: PHASE1 Type: interventional Locations: Harbin, Heilongjiang, China

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