Clinical Trials for Advanced Solid Malignancies

Find clinical trials for advanced solid malignancies. Discover research opportunities and treatment options in your area.

8 Active Trials Found

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A Study of Amivantamab Subcutaneous (SC) Administration for the Treatment of Advanced Solid Malignancies

NCT ID: NCT04606381

This clinical trial is investigating a new way to administer a medication called amivantamab for patients with advanced solid tumors, which are types of cancer that have spread and cannot be surgic...

Recruiting

Phase: PHASE1 Type: interventional Locations: Toronto, Ontario, Canada, Nashville, Tennessee, United States +16 more

Modular Clinical Pharmacology Study to Evaluate the Drug-drug Interaction Potential and Relative Bioavailability of Saruparib

NCT ID: NCT06899061

This clinical trial is studying a drug called saruparib to see how it interacts with other treatments in patients who have advanced solid tumors, which are types of cancer that have spread and cann...

Recruiting

Phase: PHASE1 Type: interventional Locations: Cluj Napoca, , Romania, Sofia, , Bulgaria +2 more

Phase I Study of the Safety, Tolerability, and Efficacy of an Engineered Mitochondrial Vaccine in Advanced Solid Tumors

NCT ID: NCT06927297

This clinical trial is investigating a new type of vaccine designed to treat patients with advanced solid tumors, like certain types of lung and colorectal cancer. The vaccine uses engineered mitoc...

Recruiting

Phase: PHASE1 Type: interventional Locations: Chengdu, Sichuan, China

Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies

NCT ID: NCT05417594

This clinical trial is studying a new drug called AZD9574 to see how safe and effective it is for people with advanced solid tumors, which are cancers that have spread or come back after treatment....

Recruiting

Phase: PHASE1 Type: interventional Locations: Barcelona, , Spain, Los Angeles, California, United States +28 more

Phase I/Ib Trial of TIraGolumab, AtEzolizumab, and RadScopal Radiation in Patients With Advanced Solid Malignancies (TIGER)

NCT ID: NCT06760481

The TIGER trial is a research study looking at a combination of three treatments—tiragolumab, atezolizumab, and RadScopal™ radiation—for patients with advanced solid tumors, which are cancers that ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

Safety and Tolerability Study of GIM-122 in Subjects With Advanced Solid Malignancies

NCT ID: NCT06028074

This clinical trial is studying a new treatment called GIM-122 for adults with advanced solid tumors, which are types of cancer that have spread and are difficult to treat. The main goal of the tri...

Recruiting

Phase: PHASE1 Type: interventional Locations: San Francisco, California, United States, Los Angeles, California, United States +10 more

A Phase I/II Study to Evaluate the Safety, Pharmacokinetics and Efficacy of PRJ1-3024 in Subjects with Advanced Solid Tumors

NCT ID: NCT05315167

This clinical trial is testing a new treatment called PRJ1-3024 for patients with advanced solid tumors, which are types of cancer that have spread and for which standard treatments are not suitabl...

Recruiting

Phase: PHASE1 Type: interventional Locations: Chengdu, Sichuan, China, Beijing, , China +3 more

A Phase I Study of BR115 for Injection Alone in Subjects With Advanced Solid Malignancies

NCT ID: NCT06388902

This clinical trial is studying a new treatment called BR115, which is being tested for the first time in people with advanced solid tumors that have not responded to standard treatments. The purpo...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Guangzhou, Guangdong, China

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