Clinical Trials for Advanced Solid Tumors

Find clinical trials for advanced solid tumors. Discover research opportunities and treatment options in your area.

212 Active Trials Found

Showing 212 trials on this page

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Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of DAT-1604 in Advanced Solid Tumor

NCT ID: NCT06998173

This clinical trial is testing a new drug called DAT-1604 to see if it is safe and can help patients with advanced solid tumors that haven’t responded to standard treatments or for which there are ...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Beijing, Beijing, China

Study to Evaluate Adverse Events, Change in Disease Activity, and How ABBV-706 Moves Through the Body When Intravenously (IV) Infused Alone or in Combination With IV Infused Budigalimab, Cisplatin, or Carboplatin in Adult Participants With Advanced Solid Tumors

NCT ID: NCT05599984

This clinical trial is studying a new drug called ABBV-706, which is being tested for its safety and effectiveness in treating advanced solid tumors, including small cell lung cancer and certain ty...

Recruiting

Phase: PHASE1 Type: interventional Locations: Grand Rapids, Michigan, United States, Oklahoma City, Oklahoma, United States +87 more

A Study of ZW191 in Participants With Solid Tumors

NCT ID: NCT06555744

This clinical trial is studying a new treatment called ZW191 for patients with advanced solid tumors, which are types of cancer that have spread and cannot be surgically removed. The trial aims to ...

Recruiting

Phase: PHASE1 Type: interventional Locations: New Haven, Connecticut, United States, Saitama, , Japan +15 more

Evaluating the Safety, Tolerability, and Preliminary Anti-tumor Activity of MB0151 in Adult Subjects With Advanced Solid Tumors Expressing Somatostatin Receptors

NCT ID: NCT06840821

This clinical trial is investigating a new treatment called MB0151 for adults with advanced solid tumors, which are types of cancers that form in various tissues or organs. The goal of the trial is...

Recruiting

Phase: PHASE1 Type: interventional Locations: Jinan, Shandong, China

PAS-004 in Patients With Advanced Solid Tumors

NCT ID: NCT06299839

This clinical trial, called PAS-004, is designed to explore a new medication for people with advanced solid tumors that have specific genetic mutations, including RAS, NF1, or RAF. The main goals a...

Recruiting

Phase: PHASE1 Type: interventional Locations: Austin, Texas, United States, San Antonio, Texas, United States +6 more

To Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetic Profile of ABN401 in Patients With Advanced Solid Tumors Harboring c-MET Dysregulation

NCT ID: NCT05541822

This clinical trial, called ABN401-003, is looking at a new treatment called ABN401 for patients with advanced solid tumors, specifically those that have certain changes in a gene known as c-MET. T...

Recruiting

Phase: PHASE2 Type: interventional Locations: Taipei, , Taiwan, Taipei City, , Taiwan +29 more

A Phase I Study of SIM0505 in Participants With Advanced Solid Tumors

NCT ID: NCT06792552

This clinical trial is testing a new treatment called SIM0505 for adults with advanced solid tumors, which are types of cancer that form in tissues or organs. The study aims to understand how safe ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Guangzhou, Guangdong, China, Guangzhou, , China +5 more

RVU120 Rollover Study

NCT ID: NCT06987058

The RVU120 Rollover Study is designed for patients with advanced solid tumors, acute myeloid leukemia, or high-risk myelodysplastic syndrome who have been receiving a treatment called RVU120 in a p...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Pamplona, , Spain, Gdańsk, , Poland

An Open-label Dose Escalation/Expansion Trial to Evaluate the Safety and Anti-tumor Activity of TEV-56278 Alone or in Combination With Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors

NCT ID: NCT06480552

This clinical trial is testing a new treatment called TEV-56278 for people with advanced solid tumors, which are cancers that have spread from their original site. The trial aims to find out how sa...

Recruiting

Phase: PHASE1 Type: interventional Locations: Huntersville, North Carolina, United States, Fairfax, Virginia, United States +8 more

A Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

NCT ID: NCT05914116

This clinical trial is studying a new drug called DB-1311 to see how safe it is and how well it works for people with advanced solid tumors, which are types of cancer that cannot be surgically remo...

Recruiting

Phase: PHASE1 Type: interventional Locations: Plantation, Florida, United States, Fairfax, Virginia, United States +102 more

Study of GS-2121 Given Alone or in Combination in Adults With Advanced Solid Tumors

NCT ID: NCT06532565

This clinical trial is studying a new treatment called GS-2121, which can be given alone or along with another drug called zimberelimab, to see how safe and effective it is for adults with advanced...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Palo Alto, California, United States +5 more

Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of TGW101 in Participants With Advanced Solid Tumors

NCT ID: NCT06959706

This clinical trial is investigating a new treatment called TGW101 for people with advanced solid tumors, which are types of cancer that form in organs or tissues, like breast, prostate, or lung. T...

Recruiting

Phase: PHASE1 Type: interventional Locations: Fairfax, Virginia, United States, San Antonio, Texas, United States +1 more

A Trial of HRS-6768 in Patients With Advanced Solid Tumors

NCT ID: NCT06925581

This clinical trial is studying a new treatment called HRS-6768 for patients with advanced solid tumors, which are cancers that cannot be easily removed and have spread to other parts of the body. ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Shanghai, Shanghai, China

Safety of Recombinant Human IL-21-expressing Oncolytic Vaccinia Virus Injection (hV01) in Advanced Tumors

NCT ID: NCT05914376

This clinical trial is testing a new treatment called hV01, an injection made from a modified virus, to see if it is safe for patients with advanced solid tumors that have not responded to standard...

Recruiting

Phase: PHASE1 Type: interventional Locations: Hangzhou, Zhejiang, China, Shanghai, , China +2 more

Study on the Safe Dosage and Therapeutic Effect of the Drug YY2201 Tablets on Patients With Advanced Cancer

NCT ID: NCT06976931

This clinical trial is studying a new drug called YY2201 to see how safe it is and how well it works for patients with advanced solid tumors, which are types of cancer that have spread beyond their...

Not yet recruiting

Phase: EARLY_PHASE1 Type: interventional

A Study of BMS-986482 Alone or as Combination Therapy in Participants With Advanced Solid Tumors

NCT ID: NCT06697197

This clinical trial is studying a new treatment called BMS-986482 for people with advanced solid tumors, which are types of cancer that cannot be surgically removed. The main goal of the study is t...

Recruiting

Phase: PHASE1 Type: interventional Locations: Hackensack, New Jersey, United States, Seattle, Washington, United States +27 more

Study to Explore the Safety, Tolerability, and Pharmacokinetics of AMG 305 in Subjects With Advanced Solid Tumors

NCT ID: NCT05800964

This clinical trial is studying a new treatment called AMG 305 for adults with advanced solid tumors, which are types of cancer that form in various organs. The main goals of the study are to see h...

Recruiting

Phase: PHASE1 Type: interventional Locations: Hackensack, New Jersey, United States, Madrid, , Spain +28 more

JAB-23E73 in Adult Participants With Advanced Solid Tumors With KRAS Alteration

NCT ID: NCT06973564

This clinical trial, called JAB-23E73, is looking at a new treatment for adults with advanced solid tumors that have specific changes in a gene known as KRAS. The goal of the study is to see if the...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Rochester, Minnesota, United States, Cleveland, Ohio, United States +2 more

A Phase Ib Study of HS-10370 in Addition to Other Anti-cancer Therapies in Patients With Advanced Solid Tumors

NCT ID: NCT06963502

This clinical trial is studying a new treatment called HS-10370, which will be tested alongside other anti-cancer therapies for patients with advanced solid tumors, particularly those with colorect...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Hangzhou, , China, Shanghai, , China

A Study of HS-10529 in KRAS G12D Patients With Advanced Solid Tumors

NCT ID: NCT06963398

This clinical trial is studying a new medication called HS-10529, which is designed for patients with advanced solid tumors that have a specific genetic change known as KRAS G12D. The goal of the s...

Not yet recruiting

Phase: PHASE1 Type: interventional

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