Clinical Trials for Breast Cancer Metastatic

Find clinical trials for breast cancer metastatic. Discover research opportunities and treatment options in your area.

40 Active Trials Found

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A Real-World Study of Elacestrant in Patients With HR+/HER2- Advanced Breast Cancer and ESR1 Mutations

NCT ID: NCT07076680

This clinical trial is studying a medicine called elacestrant in people with advanced breast cancer that is hormone receptor-positive (HR+) and HER2-negative (HER2-), and who have a specific change...

Recruiting

Type: observational Locations: Guangzhou, , China

Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer

NCT ID: NCT05735080

This clinical trial is studying a new oral medication called INX-315, which is being developed to treat advanced cancers, specifically hormone receptor-positive breast cancer and certain types of o...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Detroit, Michigan, United States +12 more

Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.

NCT ID: NCT06072612

This clinical trial is exploring a new treatment approach for patients with advanced metastatic breast cancer, which is breast cancer that has spread to other parts of the body and for which there ...

Recruiting

Phase: PHASE3 Type: interventional Locations: Chicago, Illinois, United States, Bakersfield, California, United States +58 more

A Study to Assess CLBR001+ABBV-461 in Subjects With Locally Advanced or Metastatic Breast Cancer

NCT ID: NCT06878248

This clinical trial is studying a new treatment combination, CLBR001 and ABBV-461, for patients with locally advanced or metastatic breast cancer. This means it’s looking at how well these two ther...

Recruiting

Phase: PHASE1 Type: interventional Locations: Buffalo, New York, United States, Charlottesville, Virginia, United States +1 more

Efficacy and Safety of DS8201 in Metastatic Breast Cancer's Treatment

NCT ID: NCT06914661

This clinical trial is studying a medication called DS8201 to see how effective and safe it is for treating metastatic breast cancer, which means the cancer has spread to other parts of the body. T...

Enrolling by invitation

Type: observational Locations: Changchun, Jilin, China

The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer

NCT ID: NCT06439693

The SAPPHO Study is a clinical trial aimed at testing a combination of drugs to treat women with a specific type of breast cancer called HER2-positive metastatic breast cancer. This study looks at ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Boston, Massachusetts, United States

SLV-154 Treatment of Metastatic Solid Tumors

NCT ID: NCT06771219

This clinical trial is studying a new treatment called SLV-154 for patients with certain types of metastatic solid tumors, which are cancers that have spread from their original site to other parts...

Recruiting

Phase: PHASE1 Type: interventional Locations: St. Louis, Missouri, United States, Saint Louis, Missouri, United States +2 more

Trial of Trastuzumab Deruxtecan in Previously Treated HER2

NCT ID: NCT06750484

This clinical trial is investigating a drug called trastuzumab deruxtecan (T-DXd) for adults with metastatic breast cancer that is HER2-negative, meaning it does not have high levels of a certain p...

Recruiting

Phase: PHASE2 Type: interventional Locations: New Haven, Connecticut, United States

A First-in-human, Clinical Trial Assessing the Safety of ES2B-C001-S01 With or Without [Adjuvant] in Patients With HER2 Expressing Metastatic Breast Cancer.

NCT ID: NCT06746688

This clinical trial is testing a new treatment called ES2B-C001, with or without another substance called Montanide, for patients with a specific type of breast cancer known as HER2-positive metast...

Recruiting

Phase: PHASE1 Type: interventional Locations: Vienna, , Austria

RADIomics to Predict HER2 Status And T-DXd Efficacy in Metastatic Breast Cancer: the RADIOSPHER2 Study

NCT ID: NCT07030569

This clinical trial, called RADIOSPHER2, is studying a new way to use medical images (like CT and PET scans) to better understand a protein called HER2 in patients with metastatic breast cancer—tha...

Recruiting

Type: observational Locations: Milan, , Italy

A Study of Abemaciclib and Radiation Therapy in People With Metastatic Breast Cancer

NCT ID: NCT06678269

This clinical trial is investigating the use of a medication called abemaciclib in combination with radiation therapy for people with metastatic breast cancer, which is cancer that has spread beyon...

Recruiting

Phase: PHASE1 Type: interventional Locations: Harrison, New York, United States, Middletown, New Jersey, United States +5 more

Detecting Tumor DNA in the Blood of HR+/HER2-low Metastatic Breast Cancer Patients to Find Candidates for T-DXd Therapy

NCT ID: NCT06680596

This clinical trial is investigating a new treatment for patients with advanced breast cancer that has spread to other parts of the body, specifically those whose tumors have low levels of a protei...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Villejuif, , France

Immun Checkpoint Washout in Patients With Invasive Ductal Breast Cancer

NCT ID: NCT07003009

This clinical trial is investigating a new method to help diagnose cancer spread in patients with invasive ductal breast cancer, which is the most common type of invasive breast cancer. The study f...

Recruiting

Phase: NA Type: interventional Locations: Istanbul, , Turkey

Prevention of Sacituzumab Govitecan-related Neutropenia in Patients With Metastatic Triple Negative Breast Cancer

NCT ID: NCT06616987

This clinical trial is investigating a new approach to help prevent a condition called neutropenia, which is a low level of a certain type of white blood cell, in patients who have metastatic tripl...

Not yet recruiting

Phase: PHASE2 Type: interventional

A Phase II Study of SHR-A1811 Combined With Radiotherapy in HER2-positive and HER2-low Breast Cancer Brain Metastases

NCT ID: NCT06975462

This clinical trial is studying a new treatment called SHR-A1811 combined with radiotherapy for women with advanced breast cancer that has spread to the brain. Specifically, it focuses on patients ...

Not yet recruiting

Phase: PHASE2 Type: interventional

A Single-arm Phase II Trial of SAcituzumab Govitecan and Trastuzumab for HER2+ Metastatic Breast Cancer After Trastuzumab dEruxtEcaN (SATEEN)

NCT ID: NCT06100874

This clinical trial, called SATEEN, is studying a combination of two medications—sacituzumab govitecan and trastuzumab (also known as Herceptin)—to see how safe and effective they are for women and...

Recruiting

Phase: PHASE2 Type: interventional Locations: Boston, Massachusetts, United States, Miami, Florida, United States +3 more

A Real World Study of Sacituzumab Govitecan

NCT ID: NCT06966141

This clinical trial is studying a treatment called Sacituzumab Govitecan for patients with metastatic breast cancer, particularly those whose cancer has spread and is not responding to standard tre...

Recruiting

Type: observational Locations: Shanghai, , China

21-gene in Elder Breast Cancer Patients With Lymph Node Metastasis

NCT ID: NCT06891651

This clinical trial is studying how a specific test, called the 21-gene assay, can help predict the chances of survival for elderly women (65 years and older) who have breast cancer that has spread...

Recruiting

Type: observational Locations: Jinan, Shandong, China

Olaparib in Combination with Vorinostat in Patients with Relapsed/Refractory And/or Metastatic Breast Cancer

NCT ID: NCT03742245

This clinical trial is investigating the safety and early effectiveness of two medications, olaparib and vorinostat, used together for patients with relapsed, refractory, or metastatic breast cance...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

Fulvestrant With Ribociclib Versus Physician's Choice Treatments Recurred After Completion of Adjuvant Cyclin-Dependent Kinase 4/6 Inhibitors in HR+, HER2- Metastatic Breast Cancer

NCT ID: NCT06849947

This clinical trial is studying a combination treatment of two drugs, fulvestrant and ribociclib, for patients with a specific type of breast cancer known as HR-positive, HER2-negative metastatic b...

Not yet recruiting

Phase: PHASE2 Type: interventional

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