Clinical Trials for Breast Neoplasms

A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)

NCT ID: NCT07060807

This clinical trial is studying a new treatment called patritumab deruxtecan for a specific type of breast cancer that is hormone receptor-positive (meaning the cancer grows in response to hormones...

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

NCT ID: NCT07114601

This clinical trial is studying a new medicine called LY4257496 to see if it is safe and effective for treating certain advanced cancers that have spread, including breast, colorectal (colon), pros...

A Study of Breast Cancer Risk Factors and Outcomes of People in Florida

NCT ID: NCT06780176

This clinical trial is focused on understanding why some people are more likely to develop breast cancer than others and how different factors may affect their outcomes. Researchers are looking at ...

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

NCT ID: NCT06312176

This clinical trial is studying a new treatment option for patients with a specific type of breast cancer called hormone receptor positive and HER2 negative (HR+/HER2-). The researchers want to see...

Preventing Dato-DXd Associated Stomatitis With Dexamethasone Mouthwash, TROPION-DM

NCT ID: NCT06974604

The TROPION-DM clinical trial is exploring a new treatment approach to help patients with advanced breast or lung cancer. Specifically, this study is looking at whether using a special mouthwash co...

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

NCT ID: NCT06966700

This clinical trial is studying a new treatment called sacituzumab tirumotecan (or sac-TMT) for people with certain types of breast cancer, specifically high-risk, early-stage triple-negative breas...

A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer

NCT ID: NCT06966453

This clinical trial is studying a new medicine called disitamab vedotin to see how safe and effective it is for treating adults with advanced breast cancer that has spread in the body. Specifically...

Korea Post Marketing Surveillance (PMS) Study of Talzenna®

NCT ID: NCT04982848

This clinical trial is studying the use of Talzenna®, a medication designed to treat advanced breast cancer in patients with a specific genetic condition known as gBRCA. The purpose of the study is...

A Phase I Study of [68Ga]Ga-DWJ155 in Patients With Breast and Lung Cancers

NCT ID: NCT07117214

This clinical trial is testing a new imaging agent called [68Ga]Ga-DWJ155 to see how well it works and how safe it is for use in adults with certain types of advanced breast cancer or advanced non-...

Preoperative Radiation Therapy and Immediate Breast Reconstruction

NCT ID: NCT06739655

The PRADAIIBE study is a clinical trial aimed at understanding how the timing of radiation therapy affects breast reconstruction outcomes for women with breast cancer. Specifically, it looks at whe...

A Non-interventional Study for Kisqali (Ribociclib) in Combination With an Aromatase Inhibitor for Adjuvant Treatment in Patients With HR+/HER2- Early Breast Cancer at High Risk of Recurrence

NCT ID: NCT06830720

This clinical trial is studying the effectiveness and safety of a medication called ribociclib when used with another drug, an aromatase inhibitor, in patients with a specific type of early breast ...

Screening Tool Artificial Intelligence-based for Predicting the Genetic Risk of BREAST Cancer

NCT ID: NCT07070128

This clinical trial is studying a new tool that uses artificial intelligence (AI) to help predict the genetic risk of developing breast cancer. The tool, created by a company called WeConecta, coll...

Study of Abemaciclib and Elacestrant in Patients With Brain Metastasis Due to ER+/HER-2- Breast Cancer

NCT ID: NCT05386108

This clinical trial is investigating a combination of two medications, abemaciclib and elacestrant, to see how well they work for patients with brain metastases from estrogen receptor-positive (ER+...

A Study of Disitamab Vedotin With Other Anticancer Drugs in Solid Tumors

NCT ID: NCT06157892

This clinical trial is looking at a new treatment option for people with advanced solid tumors, specifically breast and gastric cancers that have a certain protein called HER2. HER2 can make these ...

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

NCT ID: NCT01042379

The I-SPY Trial is a research study aimed at finding out which new medications work best for different types of breast cancer. The goal is to personalize treatment by looking at how tumors respond ...

A Study of Mesothelin-Targeted CAR T-Cell Therapy in People With Esophagogastric Cancer

NCT ID: NCT06623396

This clinical trial is studying a new type of treatment called mesothelin-targeted CAR T-cell therapy for people with certain types of esophagogastric cancer, which includes esophageal adenocarcino...

Breast Cancer, Reasoning, and Activity Intervention

NCT ID: NCT04816006

This clinical trial is looking at how exercise can help improve thinking and memory skills in women who have survived breast cancer. Many survivors notice difficulties with their thinking abilities...

Impact of Erector Spinae Plane Block on Chronic Postsurgical Pain in Breast Cancer Patients

NCT ID: NCT05494502

This clinical trial is studying a method called the Erector Spinae Plane Block (ESPB) to see if it can help reduce chronic pain that some breast cancer patients experience after surgery, specifical...

(Z)-Endoxifen for the Treatment of Premenopausal Women With ER+/HER2- Breast Cancer

NCT ID: NCT05607004

This clinical trial is investigating a new treatment called (Z)-endoxifen for premenopausal women with a specific type of breast cancer known as estrogen-receptor-positive and HER2-negative (ER+/HE...

Adaptive Chemotherapy for the Treatment of Advanced Breast Cancer

NCT ID: NCT07088263