Clinical Trials for Breast Neoplasms

Find clinical trials for breast neoplasms. Discover research opportunities and treatment options in your area.

140 Active Trials Found

Showing 140 trials on this page

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Korea Post Marketing Surveillance (PMS) Study of Talzenna®

NCT ID: NCT04982848

This clinical trial is studying the use of Talzenna®, a medication designed to treat advanced breast cancer in patients with a specific genetic condition known as gBRCA. The purpose of the study is...

Not yet recruiting

Type: observational

A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)

NCT ID: NCT07060807

This clinical trial is studying a new treatment called patritumab deruxtecan for a specific type of breast cancer that is hormone receptor-positive (meaning the cancer grows in response to hormones...

Phase: PHASE3 Type: interventional Locations: Tainan, Taiwan, Houston, Texas, United States +2 more

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

NCT ID: NCT06966700

This clinical trial is studying a new treatment called sacituzumab tirumotecan (or sac-TMT) for people with certain types of breast cancer, specifically high-risk, early-stage triple-negative breas...

Phase: PHASE3 Type: interventional Locations: Hialeah, Florida, United States, Baltimore, Maryland, United States +10 more

Study of Patritumab Deruxtecan Plus Pembrolizumab With Other Anticancer Agents in Participants With High-Risk Early-Stage Triple-Negative or Hormone Receptor-Low Positive/HER-2 Negative Breast Cancer (MK-1022-010, HERTHENA-Breast-03)

NCT ID: NCT06797635

This clinical trial, called HERTHENA-Breast-03, is exploring new treatment options for patients with high-risk early-stage breast cancer, specifically those with triple-negative breast cancer (TNBC...

Phase: PHASE2 Type: interventional Locations: Nashville, Tennessee, United States, Skokie, Illinois, United States +4 more

Study of Patritumab Deruxtecan With Other Anticancer Agents in Participants With HER2 Positive Breast Cancer That Has Spread and Cannot Be Surgically Removed (MK-1022-009)

NCT ID: NCT06686394

This clinical trial is studying a new treatment called patritumab deruxtecan for patients with a specific type of breast cancer known as HER2 positive breast cancer. This type of cancer is locally ...

Phase: PHASE1 Type: interventional Locations: Greenville, South Carolina, United States, Haifa, Israel +9 more

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

NCT ID: NCT06312176

This clinical trial is studying a new treatment option for patients with a specific type of breast cancer called hormone receptor positive and HER2 negative (HR+/HER2-). The researchers want to see...

Phase: PHASE3 Type: interventional Locations: Warszawa, Mazowieckie, Poland, Kielce, Swietokrzyskie, Poland +284 more

PROVIDENCE - Prospective Non-interventional Study (NIS) to Examine Patient-reported Outcomes and Real-world Clinical Data in Patients With HER2-positive, HER2-low or HER2-ultralow Unresectable or Metastatic Breast Cancer Treated With Trastuzumab Deruxtecan

NCT ID: NCT05573893

The PROVIDENCE trial is a study that aims to understand how well a medication called trastuzumab deruxtecan (T-DXd) works for patients with certain types of breast cancer. Specifically, it focuses ...

Type: observational Locations: Augsburg, Germany, Bonn, Germany +113 more

DPYD Pharmacogenomics and Fluoropyrimidine (FP) Dose-Adjustment

NCT ID: NCT07158164

This study tests whether using a patient’s DPYD gene test to guide chemo dosing can lower the risk of serious side effects from common stomach/intestinal cancer drugs (5-FU and Capecitabine) when t...

Not yet recruiting

Phase: PHASE4 Type: interventional

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

NCT ID: NCT07114601

This clinical trial is studying a new medicine called LY4257496 to see if it is safe and effective for treating certain advanced cancers that have spread, including breast, colorectal (colon), pros...

Phase: PHASE1 Type: interventional Locations: Detroit, Michigan, United States, Toronto, Ontario, Canada +12 more

A Study of Breast Cancer Risk Factors and Outcomes of People in Florida

NCT ID: NCT06780176

This clinical trial is focused on understanding why some people are more likely to develop breast cancer than others and how different factors may affect their outcomes. Researchers are looking at ...

Type: observational Locations: Miami, Florida, United States, New York, New York, United States +1 more

A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer

NCT ID: NCT06966453

This clinical trial is studying a new medicine called disitamab vedotin to see how safe and effective it is for treating adults with advanced breast cancer that has spread in the body. Specifically...

Phase: PHASE1 Type: interventional Locations: Glendale, California, United States, Los Angeles, California, United States +4 more

Preventing Dato-DXd Associated Stomatitis With Dexamethasone Mouthwash, TROPION-DM

NCT ID: NCT06974604

The TROPION-DM clinical trial is exploring a new treatment approach to help patients with advanced breast or lung cancer. Specifically, this study is looking at whether using a special mouthwash co...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Providence, Rhode Island, United States

A Phase I Study of [68Ga]Ga-DWJ155 in Patients With Breast and Lung Cancers

NCT ID: NCT07117214

This clinical trial is testing a new imaging agent called [68Ga]Ga-DWJ155 to see how well it works and how safe it is for use in adults with certain types of advanced breast cancer or advanced non-...

Not yet recruiting

Phase: PHASE1 Type: interventional

Preoperative Radiation Therapy and Immediate Breast Reconstruction

NCT ID: NCT06739655

The PRADAIIBE study is a clinical trial aimed at understanding how the timing of radiation therapy affects breast reconstruction outcomes for women with breast cancer. Specifically, it looks at whe...

Phase: NA Type: interventional Locations: Edegem, Antwerpen, Belgium, Wilrijk, Antwerpen, Belgium +3 more

A Non-interventional Study for Kisqali (Ribociclib) in Combination With an Aromatase Inhibitor for Adjuvant Treatment in Patients With HR+/HER2- Early Breast Cancer at High Risk of Recurrence

NCT ID: NCT06830720

This clinical trial is studying the effectiveness and safety of a medication called ribociclib when used with another drug, an aromatase inhibitor, in patients with a specific type of early breast ...

Type: observational Locations: Augsburg, Germany, Essen, Germany +179 more

Screening Tool Artificial Intelligence-based for Predicting the Genetic Risk of BREAST Cancer

NCT ID: NCT07070128

This clinical trial is studying a new tool that uses artificial intelligence (AI) to help predict the genetic risk of developing breast cancer. The tool, created by a company called WeConecta, coll...

Not yet recruiting

Type: observational Locations: Goiânia, Go, Brazil, Porto Alegre, Rs, Brazil

Study of Abemaciclib and Elacestrant in Patients With Brain Metastasis Due to ER+/HER-2- Breast Cancer

NCT ID: NCT05386108

This clinical trial is investigating a combination of two medications, abemaciclib and elacestrant, to see how well they work for patients with brain metastases from estrogen receptor-positive (ER+...

Phase: PHASE1 Type: interventional Locations: Urbana, Illinois, United States, Boston, Massachusetts, United States +100 more

A Study of Disitamab Vedotin With Other Anticancer Drugs in Solid Tumors

NCT ID: NCT06157892

This clinical trial is looking at a new treatment option for people with advanced solid tumors, specifically breast and gastric cancers that have a certain protein called HER2. HER2 can make these ...

Phase: PHASE2 Type: interventional Locations: Tampa, Florida, United States, Saint Louis, Missouri, United States +156 more

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

NCT ID: NCT01042379

The I-SPY Trial is a research study aimed at finding out which new medications work best for different types of breast cancer. The goal is to personalize treatment by looking at how tumors respond ...

Phase: PHASE2 Type: interventional Locations: Rochester, Minnesota, United States, Los Angeles, California, United States +35 more

Breast Cancer, Reasoning, and Activity Intervention

NCT ID: NCT04816006

This clinical trial is looking at how exercise can help improve thinking and memory skills in women who have survived breast cancer. Many survivors notice difficulties with their thinking abilities...

Phase: NA Type: interventional Locations: Scottsdale, Arizona, United States, Scottsdale, Arizona, United States +2 more

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